Effects of glial cell line-derived neurotrophic factor intrathecal injection on spinal dorsal horn glial fibrillary acidic protein expression in a rat model of neuropathic pain

J Guo, D Jia, B Jin, F Xu, X Yuan… - International Journal of …, 2012 - Taylor & Francis
Glial fibrillary acidic protein (GFAP) is a specific astrocytic marker in the central nervous
system. Few studies on the effects of glial cell line-derived neurotrophic factor (GDNF) …

[HTML][HTML] Overexpression of GDNF in the uninjured DRG exerts analgesic effects on neuropathic pain following segmental spinal nerve ligation in mice

K Takasu, A Sakai, H Hanawa, T Shimada, H Suzuki - The Journal of Pain, 2011 - Elsevier
Glial cell line-derived neurotrophic factor (GDNF), a survival-promoting factor for a subset of
nociceptive small-diameter neurons, has been shown to exert analgesic effects on …

Expression changes of glial cell line-derived neurotrophic factor in a rat model of neuropathic pain

N Takahashi, M Nagano, H Suzuki… - Journal of Medical and …, 2003 - jstage.jst.go.jp
To reveal roles of neurotrophic factors in plastic changes of the primary afferent neurons
following nerve injury, we investigated expression of glial cell line-derived neurotrophic …

Glial cell line-derived neurotrophic factor contributes to delayed inflammatory hyperalgesia in adjuvant rat pain model

M Fang, Y Wang, QH He, YX Sun, LB Deng, XM Wang… - Neuroscience, 2003 - Elsevier
Neurotrophic factors, such as nerve growth factor and brain-derived neurotrophic factor, are
members of the structurally related neurotrophin family that play important roles in pain …

Decreased expression of glial cell line‐derived neurotrophic factor signaling in rat models of neuropathic pain

M Nagano, A Sakai, N Takahashi… - British Journal of …, 2003 - Wiley Online Library
In an attempt to clarify whether glial cell line‐derived neurotrophic factor (GDNF), a survival
factor for subpopulations of primary afferent neurons, is involved in the states of neuropathic …

Expression of glial cell line-derived neurotrophic factor in the human intervertebral disc

J Yamada, K Akeda, T Sano, T Iwasaki, N Takegami… - Spine, 2020 - journals.lww.com
Study Design. Biochemical and immunohistochemical analyses by the human intervertebral
disc (IVD) cells and tissues. Objective. To examine the expression of glial cell line-derived …

Glial cell line-derived neurotrophic factor is increased in cerebrospinal fluid but decreased in blood during long-term pain

C Lundborg, M Hahn-Zoric, B Biber… - Journal of …, 2010 - Elsevier
Glial cell line-derived neurotrophic factor (GDNF) is involved in inflammation and pain, roles
which remain to be delineated clinically. We aimed to evaluate the role of central nervous …

Anti-fibroblast growth factor-2 antibodies attenuate mechanical allodynia in a rat model of neuropathic pain

F Madiai, VM Goettl, SR Hussain, AR Clairmont… - Journal of molecular …, 2005 - Springer
Peripheral nerve injury leads to the activation of spinal cord astrocytes, which contribute to
maintaining neuropathic (NP) pain behavior. Fibroblast growth factor-2 (FGF-2), a …

Cerebrospinal fluid levels of glial cell-derived neurotrophic factor correlate with spinal cord stimulation frequency in patients with neuropathic pain: a preliminary report

KF McCarthy, C McCrory - Spinal Cord, 2014 - nature.com
Study design: Case series. Objectives: To evaluate relationships between spinal cord
stimulation (SCS) parameters and levels of glial cell-derived neurotrophic factor (GDNF) …

Decreased GDNF mRNA expression in dorsal spinal cord of unilateral arthritic rat

M Fang, Y Wang, HX Liu, XS Liu, JS Han - Neuroreport, 2000 - journals.lww.com
It is now well established that nerve growth factor (NGF) plays a key role in inflammation-
induced hyperalgesia. It was also reported that brain derived neurotrophic factor (BDNF) …