Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pneumonia with
a median survival time of 2-4 years after diagnosis. The alarming mortality rate is due to the …

Idiopathic pulmonary fibrosis (IPF) is a fatal disease with limited treatment options. The role
of the developmental transcription factor Sine oculis homeobox homolog 1 (SIX1) in the …

Idiopathic pulmonary fibrosis (IPF) is a chronic, irreversible interstitial lung disease with no
curative therapies. Median survival is 3-4 years after diagnosis, and the pathogenesis of IPF …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a spontaneously occurring chronic and
irreversible lung disease with limited treatment options and poor survival rates …

Identification of Paired-related Homeobox Protein 1 as a key mesenchymal transcription factor
in Idiopathic Pulmonary Fibrosis Page 1 1 Identification of Paired-related Homeobox Protein 1 …

Rationale Idiopathic pulmonary fibrosis (IPF) is a devasting disease with a worse prognosis
than most cancers. Studies in familial IPF have implicated loss of function mutations in …

Background: Idiopathic pulmonary fibrosis (IPF) is a rare form of immune-mediated
interstitial lung disease characterized by progressive pulmonary fibrosis and scarring. The …

Pulmonary fibrosis is a pathological manifestation of dysregulated cellular and molecular
responses during injury, inflammation, and oxidative stress, progressing beyond recovery …

Idiopathic pulmonary fibrosis (IPF) is a progressive and usually lethal disease of unknown
aetiology. A growing body of evidence supports that IPF represents an epithelial-driven …

Six1 is a member of the six-homeodomain family of transcription factors. Six1 is expressed in
multiple embryonic cell types and plays important roles in proliferation, differentiation and …