Inhaled nitric oxide (iNO) is one of the most promising therapies used in neonates, but there
is little information available about its effect on the developing brain. We explored the effects …

White matter damage (WMD) and bronchopulmonary dysplasia (BPD) are the two main
complications occurring in very preterm infants. Inhaled nitric oxide (iNO) has been …

Nitric oxide (NO) has critical roles in a wide variety of key biologic functions and has intricate
transport mechanisms for delivery to key distal tissues under normal conditions. However …

Nitric oxide (NO) produced by inducible NO synthase contributes to ischemic brain damage.
However, the role of inducible NO synthase-derived NO on neonatal hypoxic-ischemic …

We hypothesized that elimination of neuronal nitric oxide synthase (nNOS) by targeted
disruption of the nNOS gene would result in amelioration of damage seen after hypoxia …

Inhaled nitric oxide (iNO) is a therapy used in neonates with pulmonary hypertension. Some
evidence of its neuroprotective properties has been reported in both mature and immature …

Apart from its known actions as a pulmonary vasodilator, nitric oxide (NO) is a key signal
mediator in the neonatal brain. Despite the extensive use of NO for pulmonary artery …

Background: Fetal growth restriction is the second leading cause of perinatal morbidity and
mortality, and neonates with intrauterine growth retardation (IUGR) have increased …

Several lines of evidence demonstrate that inhaled nitric oxide (iNO) not only acts locally on
the pulmonary vasculature but also has remote effects on the mature and developing brain …

Publisher Summary Nitric oxide (NO) is an important cellular messenger that helps regulate
cerebral blood flow and can modulate synaptic plasticity. NO is the only known biological …