Combined oral contraceptives may activate the contact system in healthy women

J Strandberg, IL Gade, Y Palarasah, JB Gram… - Research and Practice …, 2023 - Elsevier
Background The contact system (CAS) is part of the coagulation system, consisting of a
group of plasma proteins stimulating inflammation, coagulation, and fibrinolysis when …

Contact factor mediated fibrinolysis is increased by the combined oral contraceptive pill

SJ Campbell, IJ Mackie, GE Robinson… - … Journal of Obstetrics …, 1993 - Wiley Online Library
Objective To study the fibrinolytic pathways and their relationship with the contact system in
women using combined oral contraceptives (COCs). Design Serial plasma samples were …

Endogenous thrombin potential changes during the first cycle of oral contraceptive use

CL Westhoff, MC Pike, S Cremers, A Eisenberger… - Contraception, 2017 - Elsevier
Objectives Venous thromboembolism (VTE) risk increases within months of combination oral
contraceptive (COC) initiation. Because elevated endogenous thrombin potential (ETP) has …

Hormonal influences on hemostasis in women

DE Trigg, MG Wood, PA Kouides… - Seminars in thrombosis …, 2011 - thieme-connect.com
Hemostasis in women is influenced by physiological changes in hormone status associated
with the menstrual cycle, pregnancy and hormone-based contraceptives, and hormone …

Effects of switching from oral to transdermal or transvaginal contraception on markers of thrombosis

JT Jensen, AE Burke, KT Barnhart, C Tillotson… - Contraception, 2008 - Elsevier
BACKGROUND: The study was conducted to determine the impact of switching from oral to
transdermal patch or vaginal ring contraception on biomarkers of thrombosis. STUDY …

Contact factors in plasma from women on oral contraception-Significance of factor XI for the measured activity of factor XII

S Fossum, NO Hoem, S Johannesen, M Korpberget… - Thrombosis research, 1994 - Elsevier
The plasma levels of contact activation factors were measured in women using a low
estrogen dose oral contraceptive (OC). Basic values for factor XII (FXII), factor XI (FXI) …

The effects of oral contraceptive usage on thrombin generation and activated protein C resistance in Saudi women, with a possible impact of the body mass index

ABO Mohamed, H Kelchtermans, J Konings… - PLoS …, 2018 - journals.plos.org
Background and objectives The effect of oral contraceptive (OC) usage on coagulation has
been studied worldwide. However, no such studies have been conducted in Saudi Arabia …

Contact activation factors in plasma from women using oral contraceptives-increased levels of factor XII, kinin-free high molecular weight kininogen and acetone …

NO Hoem, S Johannesen, G Hauge, AC Rud… - Thrombosis research, 1991 - Elsevier
The plasma levels of FXII, prekallikrein (PK) and high-and low molecular weight kininogens
(HK and LK) were measured in women on low estrogen dose (30–40 μg ethinylestradiol) …

Oral versus vaginal combined hormonal contraceptives' effect on coagulation and inflammatory biomarkers among young adult women

AA Divani, X Luo, KR Brandy… - Clinical and Applied …, 2012 - journals.sagepub.com
In order to compare the effect of combined oral contraceptive (COC) and combined vaginal
contraceptive (CVC) methods on the inflammation and procoagulation, we recruited female …

Impact of hormone-associated resistance to activated protein C on the thrombotic potential of oral contraceptives: a prospective observational study

H Rühl, L Schröder, J Müller, S Sukhitashvili, J Welz… - PLoS …, 2014 - journals.plos.org
Introduction The increased thrombotic risk of oral contraceptives (OC) has been attributed to
various alterations of the hemostatic system, including acquired resistance to activated …