Oral contraceptives, thrombosis and haemostasis

J Rosing, J Curvers, G Tans - European Journal of Obstetrics & Gynecology …, 2001 - Elsevier
The use of oral contraceptives is a well-established acquired risk factor for venous
thrombosis. In 1995, a number of epidemiological studies were published which suggested …

Oral contraceptive use is associated with a systemic acute phase response

M Fröhlich, A Döring, A Imhof, WL Hutchinson… - Fibrinolysis and …, 1999 - Elsevier
Objective: We determined whether reported intake of oral contraceptives is associated with
an acute phase response, since inflammation is important in atherogenesis and may …

[HTML][HTML] Different effects of oral contraceptives containing different progestogens on protein S and tissue factor pathway inhibitor

H Van Vliet, RM Bertina, AEA Dahm… - Journal of Thrombosis …, 2008 - Elsevier
Background: Oral contraceptives (OC) containing different types of progestogens induce
different sensitivities to activated protein C (APC) measured with the thrombin generation …

Effects of third-generation oral contraceptives on high-sensitivity C-reactive protein and homocysteine in young women

S Cauci, M Di Santolo, JF Culhane, G Stel… - Obstetrics & …, 2008 - journals.lww.com
OBJECTIVE: To evaluate the effect of third-generation oral contraceptives on high-sensitivity
C-reactive protein (CRP), homocysteine, and lipids levels in a population of young, fertile …

[HTML][HTML] Sex hormone‐binding globulin as a marker for the thrombotic risk of hormonal contraceptives

M Raps, F Helmerhorst, K Fleischer… - Journal of Thrombosis …, 2012 - Elsevier
Background: It takes many years to obtain reliable values for the risk of venous thrombosis of
hormonal contraceptive users from clinical data. Measurement of activated protein C (APC) …

Clotting factor changes during the first cycle of oral contraceptive use

CL Westhoff, A Eisenberger, R Tang, S Cremers… - Contraception, 2016 - Elsevier
Objectives The risk of venous thromboembolism (VTE) is highest during the initial months of
oral contraceptive (OC) use. We sought to evaluate the extent of hemostatic variable …

Thrombosis in Young Women on Ocps Likely Is Caused By an Unmasking Effect of Estrogens on Underlying Thrombophilias

Z He, D Thornhill, C Baird, A Tran, R Shearer… - Blood, 2023 - Elsevier
Background: Estrogen-containing oral contraceptives (OCPs) increase the risk for
thrombosis 3-4 fold in otherwise healthy young women, although the absolute thrombosis …

Prothrombotic effects and clinical implications of third-generation oral contraceptives use

G Lippi, F Manzato, G Brocco… - Blood coagulation & …, 2002 - journals.lww.com
Although the use of oral contraceptives has been frequently associated with an increased
risk of thromboembolic events, definitive prothrombotic mechanisms have not so far been …

Predictive value for increased activated factor XI activity in acute venous thromboembolism

M Nagy, AP Robles, M Visser, T Koeck… - Journal of Thrombosis …, 2023 - Elsevier
Background Venous thromboembolism (VTE) is associated with excessive coagulation
activity, which in part can be attributed to activation of contact system. However, the …

[HTML][HTML] Impact of progestagens on activated protein C (APC) resistance among users of oral contraceptives

M Alhenc‐Gelas, G Plu‐Bureau, S Guillonneau… - Journal of thrombosis …, 2004 - Elsevier
Oral contraceptive (OC) use is associated with an increased risk of venous
thromboembolism. Previous data reported higher thrombotic risk in women using third …