Key points Although lipid droplets in skeletal muscle are an important energy source during
endurance exercise, our understanding of lipid metabolism in this context remains …

The skeletal muscle is subjected to high mechanical and energetic demands. Lipid droplets
are an important source of energy substrates for the working muscle. Muscle cells contain a …

Objective Intramyocellular lipid (IMCL) storage negatively associates with insulin resistance,
albeit not in endurance-trained athletes. We investigated the putative contribution of lipid …

Conventionally viewed as energy storage depots, lipid droplets (LDs) play a central role in
muscle lipid metabolism and intracellular signaling, as recognized by recent advances in …

Purpose Smaller lipid droplet morphology and GLUT 4 protein expression have been
associated with greater muscle oxidative capacity and glucose uptake, respectively. The …

Both stable isotope methodology and fluorescence microscopy were applied to define the
use of intramuscular triglyceride (IMTG) stores as a substrate source during exercise on a …

Bipsies were obtained from the gastrocnemius muscle of 13 male and 12 female distance
runners and analyzed for [14C] palmitoyl-CoA oxidation, fiber composition, and the activities …

In skeletal muscle, an accumulation of lipid droplets (LDs) in the subsarcolemmal space is
associated with insulin resistance, but the underlying mechanism is not clear. We aimed to …

Key points Muscle glycogen and intramuscular triglycerides (IMTG, stored in lipid droplets)
are important energy substrates during prolonged exercise. Exercise‐induced changes in …

Triglycerides are stored within lipid droplets in skeletal muscle and can be hydrolyzed to
produce fatty acids for energy production through β-oxidation and oxidative phosphorylation …