mRNA-based vaccines and therapeutics: An in-depth survey of current and upcoming clinical applications
YS Wang, M Kumari, GH Chen, MH Hong… - Journal of Biomedical …, 2023 - Springer
Abstract mRNA-based drugs have tremendous potential as clinical treatments, however, a
major challenge in realizing this drug class will promise to develop methods for safely …
major challenge in realizing this drug class will promise to develop methods for safely …
The clinical progress of mRNA vaccines and immunotherapies
The emergency use authorizations (EUAs) of two mRNA-based severe acute respiratory
syndrome coronavirus (SARS-CoV)-2 vaccines approximately 11 months after publication of …
syndrome coronavirus (SARS-CoV)-2 vaccines approximately 11 months after publication of …
Opportunities and challenges in the delivery of mRNA-based vaccines
In the past few years, there has been increasing focus on the use of messenger RNA
(mRNA) as a new therapeutic modality. Current clinical efforts encompassing mRNA-based …
(mRNA) as a new therapeutic modality. Current clinical efforts encompassing mRNA-based …
mRNA vaccines in disease prevention and treatment
G Zhang, T Tang, Y Chen, X Huang… - Signal transduction and …, 2023 - nature.com
Abstract mRNA vaccines have emerged as highly effective strategies in the prophylaxis and
treatment of diseases, thanks largely although not totally to their extraordinary performance …
treatment of diseases, thanks largely although not totally to their extraordinary performance …
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
N Chaudhary, D Weissman… - Nature reviews Drug …, 2021 - nature.com
Over the past several decades, messenger RNA (mRNA) vaccines have progressed from a
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …
mRNA as a transformative technology for vaccine development to control infectious diseases
G Maruggi, C Zhang, J Li, JB Ulmer, D Yu - Molecular Therapy, 2019 - cell.com
In the last two decades, there has been growing interest in mRNA-based technology for the
development of prophylactic vaccines against infectious diseases. Technological …
development of prophylactic vaccines against infectious diseases. Technological …
[HTML][HTML] mRNA vaccines—a new era in vaccinology
Abstract mRNA vaccines represent a promising alternative to conventional vaccine
approaches because of their high potency, capacity for rapid development and potential for …
approaches because of their high potency, capacity for rapid development and potential for …
A comprehensive review of mRNA vaccines
mRNA vaccines have been demonstrated as a powerful alternative to traditional
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …
Advances in mRNA vaccines for infectious diseases
C Zhang, G Maruggi, H Shan, J Li - Frontiers in immunology, 2019 - frontiersin.org
During the last two decades, there has been broad interest in RNA-based technologies for
the development of prophylactic and therapeutic vaccines. Preclinical and clinical trials have …
the development of prophylactic and therapeutic vaccines. Preclinical and clinical trials have …