The gut-brain axis, the human gut microbiota and their integration in the development of obesity

ES Bliss, E Whiteside - Frontiers in physiology, 2018 - frontiersin.org
Obesity is a global epidemic, placing socioeconomic strain on public healthcare systems,
especially within the so-called Western countries, such as Australia, United States, United …

Role of the gut–brain axis in energy and glucose metabolism

HR Wachsmuth, SN Weninger, FA Duca - Experimental & molecular …, 2022 - nature.com
The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

The microbiota and the gut–brain axis in controlling food intake and energy homeostasis

M Romaní-Pérez, C Bullich-Vilarrubias… - International journal of …, 2021 - mdpi.com
Obesity currently represents a major societal and health challenge worldwide. Its prevalence
has reached epidemic proportions and trends continue to rise, reflecting the need for more …

The role of the gut microbiota in the gut–brain axis in obesity: mechanisms and future implications

J van Son, LL Koekkoek, SE La Fleur, MJ Serlie… - International Journal of …, 2021 - mdpi.com
Interaction between the gut and the brain is essential for energy homeostasis. In obesity, this
homeostasis is disrupted, leading to a positive energy balance and weight gain. Obesity is a …

Regulation of energy balance by a gut–brain axis and involvement of the gut microbiota

PV Bauer, SC Hamr, FA Duca - Cellular and molecular life sciences, 2016 - Springer
Despite significant progress in understanding the homeostatic regulation of energy balance,
successful therapeutic options for curbing obesity remain elusive. One potential target for the …

A review on the role of food-derived bioactive molecules and the microbiota–gut–brain axis in satiety regulation

NA Pizarroso, P Fuciños, C Gonçalves, L Pastrana… - Nutrients, 2021 - mdpi.com
Obesity is a chronic disease resulting from an imbalance between energy intake and
expenditure. The growing relevance of this metabolic disease lies in its association with …

Gut microbiota, nutrient sensing and energy balance

FA Duca, TKT Lam - Diabetes, Obesity and Metabolism, 2014 - Wiley Online Library
The gastrointestinal (GI) tract is a highly specialized sensory organ that provides crucial
negative feedback during a meal, partly via a gut–brain axis. More specifically …

Obesity and gut–microbiota–brain axis: A narrative review

A Asadi, N Shadab Mehr, MH Mohamadi… - Journal of clinical …, 2022 - Wiley Online Library
Introduction Obesity is a major health problem that is associated with many physiological
and mental disorders, such as diabetes, stroke, and depression. Gut microbiota has been …

Gut microbes and health: a focus on the mechanisms linking microbes, obesity, and related disorders

M Rastelli, C Knauf, PD Cani - Obesity, 2018 - Wiley Online Library
The past decade has been characterized by tremendous progress in the field of the gut
microbiota and its impact on host metabolism. Although numerous studies show a strong …

Interplay between the gut-brain axis, obesity and cognitive function

A Agustí, MP García-Pardo, I López-Almela… - Frontiers in …, 2018 - frontiersin.org
Obesity continues to be one of the major public health problems due to its high prevalence
and co-morbidities. Common co-morbidities not only include cardiometabolic disorders but …