Co-occurring microflora and mucin drive Pseudomonas aeruginosa diversification and pathoadaptation
While several environmental factors contribute to the evolutionary diversification of the
pathogenic bacterium Pseudomonas aeruginosa during cystic fibrosis lung infections …
pathogenic bacterium Pseudomonas aeruginosa during cystic fibrosis lung infections …
Rapid diversification of Pseudomonas aeruginosa in cystic fibrosis lung-like conditions
Chronic infection of the cystic fibrosis (CF) airway by the opportunistic pathogen
Pseudomonas aeruginosa is the leading cause of morbidity and mortality for adult CF …
Pseudomonas aeruginosa is the leading cause of morbidity and mortality for adult CF …
Niche, not phylogeny, governs the response to oxygen availability among diverse Pseudomonas aeruginosa strains
S Shewaramani, R Kassen - Frontiers in Microbiology, 2022 - frontiersin.org
Pseudomonas aeruginosa, a ubiquitous opportunistic pathogen, is a leading cause of
chronic infection of airways in cystic fibrosis (CF) patients. Chronic infections typically arise …
chronic infection of airways in cystic fibrosis (CF) patients. Chronic infections typically arise …
Pseudomonas aeruginosa evolutionary adaptation and diversification in cystic fibrosis chronic lung infections
Pseudomonas aeruginosa populations undergo a characteristic evolutionary adaptation
during chronic infection of the cystic fibrosis (CF) lung, including reduced production of …
during chronic infection of the cystic fibrosis (CF) lung, including reduced production of …
Microevolution of Pseudomonas aeruginosa to a Chronic Pathogen of the Cystic Fibrosis Lung
M Hogardt, J Heesemann - Between pathogenicity and commensalism, 2012 - Springer
Pseudomonas aeruginosa is the leading pathogen of chronic cystic fibrosis (CF) lung
infection. Life-long persistance of P. aeruginosa in the CF lung requires a sophisticated …
infection. Life-long persistance of P. aeruginosa in the CF lung requires a sophisticated …
Cystic Fibrosis-Niche Adaptation of Pseudomonas aeruginosa Reduces Virulence in Multiple Infection Hosts
The opportunistic pathogen Pseudomonas aeruginosa is able to thrive in diverse ecological
niches and to cause serious human infection. P. aeruginosa environmental strains are …
niches and to cause serious human infection. P. aeruginosa environmental strains are …
Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection
Abstract The Cystic Fibrosis (CF) lung harbors a complex, polymicrobial ecosystem, in which
Pseudomonas aeruginosa is capable of sustaining chronic infections, which are highly …
Pseudomonas aeruginosa is capable of sustaining chronic infections, which are highly …
Evolutionary diversification of Pseudomonas aeruginosa in an artificial sputum model
Background During chronic lung infections of cystic fibrosis patients Pseudomonas
aeruginosa populations undergo extensive evolutionary diversification. However, the …
aeruginosa populations undergo extensive evolutionary diversification. However, the …
The role of multispecies social interactions in shaping Pseudomonas aeruginosa pathogenicity in the cystic fibrosis lung
S O'Brien, JL Fothergill - FEMS microbiology letters, 2017 - academic.oup.com
Pseudomonas aeruginosa is a major pathogen in the lungs of cystic fibrosis (CF) patients.
However, it is now recognised that a diverse microbial community exists in the airways …
However, it is now recognised that a diverse microbial community exists in the airways …
Environmental heterogeneity drives within-host diversification and evolution of Pseudomonas aeruginosa
T Markussen, RL Marvig, M Gómez-Lozano, K Aanæs… - MBio, 2014 - Am Soc Microbiol
Microbial population polymorphisms are commonly observed in natural environments,
including long-term infected hosts. However, the underlying processes promoting and …
including long-term infected hosts. However, the underlying processes promoting and …