[HTML][HTML] Inhibitory actions of genistein in human breast cancer (MCF-7) cells

WF Chen, MH Huang, CH Tzang, M Yang… - Biochimica et Biophysica …, 2003 - Elsevier
Genistein, a natural isoflavanoid phytoestrogen, is thought to be the active ingredient in soy
that possesses breast cancer preventive properties. The molecular mechanisms that are …

Estrogenic Effects of Genistein on the Growth of Estrogen Receptor-positive Human Breast Cancer (MCF-7) Cells in Vitro and in Vivo

CY Hsieh, RC Santell, SZ Haslam, WG Helferich - Cancer research, 1998 - AACR
Genistein, found in soy products, is a phytochemical with several biological activities. In the
current study, our research focused on the estrogenic and proliferation-inducing activity of …

Genistein exerts multiple suppressive effects on human breast carcinoma cells

ZM Shao, J Wu, ZZ Shen, SH Barsky - Cancer Research, 1998 - AACR
Dietary genistein, a natural flavone compound found in soy, has been proposed to be
responsible for the low rate of breast cancer in Asian women. The cellular mechanisms of …

Effective chemopreventive activity of genistein against human breast cancer cells

YH Shon, SD Park, KS Nam - BMB Reports, 2006 - koreascience.kr
Chemopreventive and cytotoxic effect of genistein against human breast cancer cell lines
was investigated. Genistein inhibited cell proliferation in estrogen receptor-positive (MCF-7) …

Genistein: a potent anti-breast cancer agent

SS Bhat, SK Prasad, C Shivamallu, KS Prasad… - Current Issues in …, 2021 - mdpi.com
Genistein is an isoflavonoid present in high quantities in soybeans. Possessing a wide
range of bioactives, it is being studied extensively for its tumoricidal effects. Investigations …

Mechanisms of cancer chemoprevention by soy isoflavone genistein

FH Sarkar, Y Li - Cancer and Metastasis Reviews, 2002 - Springer
Diet has been implicated to play an important role in cancers. Epidemiological studies have
revealed that Asians, who consume a traditional diet high in soy products, have relatively …

Molecular effects of genistein on estrogen receptor mediated pathways

TTY Wang, N Sathyamoorthy, JM Phang - Carcinogenesis, 1996 - academic.oup.com
Genistein, a component of soy products, may play a role in the prevention of breast and
prostate cancer. However, little is known about the molecular mechanisms involved. In the …

Genistein, a potential phytochemical against breast cancer treatment-insight into the molecular mechanisms

M Sohel, P Biswas, M Al Amin, MA Hossain, H Sultana… - Processes, 2022 - mdpi.com
Breast cancer (BC) is one of the most common malignancies in women. Although
widespread successful synthetic drugs are available, natural compounds can also be …

Genistein-induced apoptosis in MCF-7 cells involves changes in Bak and Bcl-x without evidence of anti-oestrogenic effects

LS Po, TT Wang, ZY Chen, LK Leung - British Journal of Nutrition, 2002 - cambridge.org
South-east Asian women have a lower rate of breast cancer compared with their
counterparts in western countries and the difference in soyabean consumption has been …

Genistein: its role in breast cancer growth and metastasis

V Mukund - Current drug metabolism, 2020 - ingentaconnect.com
Background: Genistein being a phytoestrogen imitates the characteristics of estrogen, which
can be useful to treat conditions by reducing the estrogen levels at the time of menopause …