[HTML][HTML] Therapeutic angiogenesis using autologous adipose-derived regenerative cells in patients with critical limb ischaemia in Japan: a clinical pilot study
T Katagiri, K Kondo, R Shibata, R Hayashida… - Scientific Reports, 2020 - nature.com
Adipose-derived regenerative cell (ADRC) is a promising alternative source of autologous
somatic stem cells for the repair of damaged tissue. This study aimed to assess the safety …
somatic stem cells for the repair of damaged tissue. This study aimed to assess the safety …
[HTML][HTML] Therapeutic angiogenesis for patients with no-option critical limb ischemia by adipose-derived regenerative cells: TACT-ADRC multicenter trial
Y Shimizu, K Kondo, R Hayashida, K Sasaki… - Angiogenesis, 2022 - Springer
Background Patients with critical limb ischemia (CLI) still have a high rate of lower limb
amputation, which is associated with not only a decrease in quality of life but also poor life …
amputation, which is associated with not only a decrease in quality of life but also poor life …
Safety and Effect of Adipose Tissue-Derived Stem Cell Implantation in Patients With Critical Limb Ischemia–A Pilot Study–
HC Lee, SG An, HW Lee, JS Park, KS Cha… - Circulation …, 2012 - jstage.jst.go.jp
Background: Treatment of critical limb ischemia (CLI) by bypass operation or percutaneous
vascular intervention is occasionally difficult. The safety and efficacy of multiple …
vascular intervention is occasionally difficult. The safety and efficacy of multiple …
[HTML][HTML] Therapeutic angiogenesis with somatic stem cell transplantation
T Murohara - Korean circulation journal, 2020 - ncbi.nlm.nih.gov
Therapeutic angiogenesis is an important strategy to rescue ischemic tissues in patients with
critical limb ischemia having no other treatment option such as endovascular angioplasty or …
critical limb ischemia having no other treatment option such as endovascular angioplasty or …
Phase I trial: the use of autologous cultured adipose-derived stroma/stem cells to treat patients with non-revascularizable critical limb ischemia
A Bura, V Planat-Benard, P Bourin, JS Silvestre… - Cytotherapy, 2014 - Elsevier
Background aims Non-revascularizable critical limb ischemia (CLI) is the most severe stage
of peripheral arterial disease, with no therapeutic option. Extensive preclinical studies have …
of peripheral arterial disease, with no therapeutic option. Extensive preclinical studies have …
Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue–derived stromal cells
H Nakagami, K Maeda, R Morishita… - … , and vascular biology, 2005 - Am Heart Assoc
Objective—The delivery of autologous progenitor cells into ischemic tissue of patients is
emerging as a novel therapeutic option. Here, we report the potential impact of cultured …
emerging as a novel therapeutic option. Here, we report the potential impact of cultured …
Therapeutic angiogenesis by autologous adipose-derived regenerative cells: comparison with bone marrow mononuclear cells
C Hao, S Shintani, Y Shimizu… - American Journal …, 2014 - journals.physiology.org
Transplantation of adipose-derived regenerative cell (ADRC) enhances ischemia-induced
angiogenesis, but the underlying mechanism remains unknown. Here, we compared the …
angiogenesis, but the underlying mechanism remains unknown. Here, we compared the …
Transplantation of freshly isolated adipose tissue-derived regenerative cells enhances angiogenesis in a murine model of hind limb ischemia
Y Harada, Y Yamamoto, S Tsujimoto… - Biomedical …, 2013 - jstage.jst.go.jp
Therapeutic angiogenesis has emerged as one of the most promising therapies for severe
ischemic cardiovascular diseases with no optional therapy. Several investigators have …
ischemic cardiovascular diseases with no optional therapy. Several investigators have …
Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis
K Kondo, S Shintani, R Shibata… - … , and vascular biology, 2009 - Am Heart Assoc
Objective—Therapeutic angiogenesis using autologous stem/progenitor cells represents a
novel strategy for severe ischemic diseases. Recent reports indicated that adipose tissues …
novel strategy for severe ischemic diseases. Recent reports indicated that adipose tissues …
[PDF][PDF] Application of adipose-derived stem cells in critical limb ischemia
K Zhi, Z Gao, J Bai, Y Wu, S Zhou… - Front Biosci (Landmark …, 2014 - article.imrpress.com
Peripheral artery disease is growing in global prevalence. Its most severe form, critical limb
ischemia (CLI), is associated with high rates of limb loss, morbidity, and mortality …
ischemia (CLI), is associated with high rates of limb loss, morbidity, and mortality …