Towards a diagnosis of cochlear neuropathy with envelope following responses

LA Shaheen, MD Valero, MC Liberman - Journal of the Association for …, 2015 - Springer
Listeners with normal audiometric thresholds can still have suprathreshold deficits, for
example, in the ability to discriminate sounds in complex acoustic scenes. One likely source …

Envelope following responses predict speech-in-noise performance in normal-hearing listeners

AM Mepani, S Verhulst, KE Hancock… - Journal of …, 2021 - journals.physiology.org
Permanent threshold elevation after noise exposure or aging is caused by loss of sensory
cells; however, animal studies show that hair cell loss is often preceded by degeneration of …

Auditory brainstem response latency in noise as a marker of cochlear synaptopathy

G Mehraei, AE Hickox, HM Bharadwaj… - Journal of …, 2016 - Soc Neuroscience
Evidence from animal and human studies suggests that moderate acoustic exposure,
causing only transient threshold elevation, can nonetheless cause “hidden hearing loss” that …

The middle ear muscle reflex in the diagnosis of cochlear neuropathy

MD Valero, KE Hancock, MC Liberman - Hearing research, 2016 - Elsevier
Cochlear neuropathy, ie the loss of auditory nerve fibers (ANFs) without loss of hair cells,
may cause hearing deficits without affecting threshold sensitivity, particularly if the subset of …

Noise-induced cochlear neuropathy is selective for fibers with low spontaneous rates

AC Furman, SG Kujawa… - Journal of …, 2013 - journals.physiology.org
Acoustic overexposure can cause a permanent loss of auditory nerve fibers without
destroying cochlear sensory cells, despite complete recovery of cochlear thresholds, as …

Individual differences in auditory brainstem response wave characteristics: relations to different aspects of peripheral hearing loss

S Verhulst, A Jagadeesh, M Mauermann… - Trends in …, 2016 - journals.sagepub.com
Little is known about how outer hair cell loss interacts with noise-induced and age-related
auditory nerve degradation (ie, cochlear synaptopathy) to affect auditory brainstem response …

[HTML][HTML] Cochlear neuropathy and the coding of supra-threshold sound

HM Bharadwaj, S Verhulst, L Shaheen… - Frontiers in systems …, 2014 - frontiersin.org
Many listeners with hearing thresholds within the clinically normal range nonetheless
complain of difficulty hearing in everyday settings and understanding speech in noise …

Investigating the effect of cochlear synaptopathy on envelope following responses using a model of the auditory nerve

G Encina-Llamas, JM Harte, T Dau… - Journal of the …, 2019 - Springer
The healthy auditory system enables communication in challenging situations with high
levels of background noise. Yet, despite normal sensitivity to pure tones, many listeners …

Effects of cochlear synaptopathy on middle-ear muscle reflexes in unanesthetized mice

MD Valero, KE Hancock, SF Maison, MC Liberman - Hearing research, 2018 - Elsevier
Cochlear synaptopathy, ie the loss of auditory-nerve connections with cochlear hair cells, is
seen in aging, noise damage, and other types of acquired sensorineural hearing loss …

Toward a diagnostic test for hidden hearing loss

CJ Plack, A Léger, G Prendergast, K Kluk… - Trends in …, 2016 - journals.sagepub.com
Cochlear synaptopathy (or hidden hearing loss), due to noise exposure or aging, has been
demonstrated in animal models using histological techniques. However, diagnosis of the …