Assessment of the exposure to tobacco-specific nitrosamines and minor tobacco alkaloids in users of various tobacco/nicotine products

G Scherer, M Scherer, J Mütze… - Chemical Research in …, 2022 - ACS Publications
Tobacco-specific nitrosamines (TSNAs), in particular, the human carcinogens 4-
(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N′-nitrosonornicotine (NNN), are …

Tobacco-specific nitrosamines in the tobacco and mainstream smoke of US commercial cigarettes

SH Edwards, LM Rossiter, KM Taylor… - Chemical research in …, 2017 - ACS Publications
Tobacco-specific nitrosamines (TSNAs) are N-nitroso-derivatives of pyridine-alkaloids (eg,
nicotine) present in tobacco and cigarette smoke. Two TSNAs, N′-nitrosonornicotine (NNN) …

Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers

D Kavvadias, G Scherer, F Cheung, G Errington… - Biomarkers, 2009 - Taylor & Francis
Tobacco-specific N-nitrosamines (TSNA) include 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK), N′-nitroso nornicotine (NNN), N′-nitroso anabasine (NAB) and N …

Metabolism and DNA adduct formation of carcinogenic tobacco-specific nitrosamines found in smokeless tobacco products

SS Hecht - Smokeless tobacco products, 2020 - Elsevier
Tobacco-specific nitrosamines are the most abundant strong carcinogens in smokeless
tobacco products. This chapter focuses on three of the most important of these compounds …

Formation and analysis of tobacco-specific N-nitrosamines

KD Brunnemann, B Prokopczyk… - Tobacco-Specific N …, 2017 - api.taylorfrancis.com
Chemical-analytical studies during the past 4 years led to several new observa tions on the
formation of tobacco-specific A-nitrosamines (TSNA) and their occurrence in smokeless …

Tobacco-specific nitrosamines: A literature review

E Konstantinou, F Fotopoulou, A Drosos… - Food and chemical …, 2018 - Elsevier
Cigarette smoke is a complex mixture of chemicals, including several tobacco-specific
nitrosamines (TSNA). Most TSNA are formed in tobacco during the post-harvest period …

Tobacco-specific nitrosamines in new tobacco products

I Stepanov, J Jensen, D Hatsukami… - Nicotine & Tobacco …, 2006 - academic.oup.com
New tobacco products, designed to attract consumers who are concerned about the health
effects of tobacco, have been appearing on the market. Objective evaluation of these …

Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers

DL Ashley, RJ O'Connor, JT Bernert, CH Watson… - … , biomarkers & prevention, 2010 - AACR
Background: Smokers are exposed to significant doses of carcinogens, including tobacco-
specific nitrosamines (TSNA). Previous studies have shown significant global differences in …

Acute and subacute effects of tobacco alkaloids, tobacco-specific nitrosamines and phenethyl isothiocyanate on N′-nitrosonornicotine metabolism in rats

S Tyroller, W Zwickenpflug, C Thalheim, E Richter - Toxicology, 2005 - Elsevier
N′-Nitrosonornicotine (NNN) was the first tobacco-specific nitrosamine (TSNA) identified as
carcinogen in tobacco smoke, but no data exist on in vivo interactions between NNN and …

Tobacco-specific N-nitrosamines in tobacco and mainstream smoke of Indian cigarettes

R Kumar, M Siddiqi, AR Tricker… - Food and chemical …, 1991 - Elsevier
Different brands of Indian cigarettes were analysed, by gas chromatography-thermal energy
analysis, for the presence of carcinogenic tobacco-specific N-nitrosamines (TSNA) in both …