Arterial and venous thrombosis constitute a major source of morbidity and mortality
worldwide. Association between thrombotic complications and cardiovascular and other …

The concept that inflammation participates pivotally in the pathogenesis of atherosclerosis
and its complications has gained considerable attention, but has not yet entered clinical …

A variety of systemic inflammatory rheumatic diseases associate with an increased risk of
atherosclerotic events and premature cardiovascular (CV) disease. Although this recognition …

Observations on human and experimental atherosclerosis, biomarker studies, and now a
large-scale clinical trial support the operation of immune and inflammatory pathways in this …

Inflammation is an important driver of atherosclerosis, and the favourable outcomes of the
Canakinumab Anti-inflammatory Thrombosis Outcome Study (CANTOS) trial revealed the …

Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction
caused by a dysregulated or over-reactive host response to infection. During sepsis, the …

Atherosclerosis represents the most common pathological substrate of coronary heart
disease (CHD), and the characterization of the disease as a chronic low-grade inflammatory …

Atherosclerosis is a chronic inflammatory process and both the innate and adaptive immune
systems 1 play central roles in its initiation and subsequent progression. 2 Experimental …

In the 15 years that have passed since C-reactive protein was linked to future cardiovascular
events in otherwise healthy individuals, 1 no alternative biomarker has proved to be a …

Thrombosis and cardiovascular complications are common manifestations of a variety of
pathological conditions, including infections and chronic inflammatory diseases. Hence …