Aims The aim of present study is to evaluate the clinical significance of the time‐dependent
changes in xanthine oxidoreductase (XOR) activity during hospitalization for acute heart …

Aims Plasma xanthine oxidoreductase (XOR) activity during the acute phase of acute heart
failure (AHF) requires further elucidation. Methods and results One hundred eighteen AHF …

Background: The factors associated with a low plasma xanthine oxidoreductase (XOR)
activity were not elucidated in patients with acute heart failure (AHF). Methods: Two-hundred …

Background Oxidative stress due to purine degradation is associated with the development
of chronic heart failure (CHF). Xanthine oxidoreductase (XOR) is a rate-limiting enzyme of …

Plasma xanthine oxidoreductase (XOR) activity in patients with cardiopulmonary arrest
(CPA) has not yet been studied. A total of 1,158 patients who required intensive care and …

Aims Reactive oxygen species are reportedly involved in the mechanism underlying heart
failure with preserved ejection fraction (HFpEF); however, the disease pathophysiology …

Hyperuricemia is known to be associated with adverse outcomes in cardiovascular intensive
care patients, but its mechanisms are unknown. A total of 569 emergency department …

Background and purpose Xanthine oxidoreductase (XOR), which catalyzes purine
catabolism, has two interconvertible forms, xanthine dehydrogenase and xanthine oxidase …

Background: The mechanisms of the increased plasma xanthine oxidoreductase (XOR)
activity in outpatients with cardiovascular disease were unclear. Methods and Results: A …

The time from cardiac arrest to return of spontaneous circulation (ROSC) has been reported
to have prognostic impact in patients with CPA. The same results were obtained in the …