[引用][C] Elevated plasma xanthine oxidase activity in chronic heart failure: Source of increased oxygen radical load and effect of allopurinol in a placebo controlled …

W Doehner, MM Tarpey, DV Pavitt, AP Bolger… - Journal of the American …, 2003 - jacc.org
Background: Elevated xanthine oxidase (X0) activity contributes to production of reactive
oxygen species. Hyperuicemia is common in chronic heart failure (CHF), however, enzyme …

Plasma xanthine oxidoreductase activity in Japanese patients with type 2 diabetes across hospitalized treatment

Y Kawachi, Y Fujishima, H Nishizawa… - Journal of diabetes …, 2021 - Wiley Online Library
Abstract Aims/Introduction Xanthine oxidoreductase (XOR) is an enzyme that catalyzes
hypoxanthine and xanthine to xanthine and uric acid, respectively. Plasma XOR activity has …

[HTML][HTML] Plasma xanthine oxidoreductase activity associated with glycemic control in patients with pre-dialysis chronic kidney disease

S Nakatani, E Ishimura, T Murase… - Kidney and Blood …, 2021 - karger.com
Introduction: Xanthine oxidoreductase (XOR) activity plays an important role as a pivotal
source of reactive oxygen species, which is associated with cardiovascular disease (CVD) …

Xanthine oxidase activity in patients with sepsis

MN Luchtemberg, F Petronilho, L Constantino… - Clinical …, 2008 - Elsevier
OBJECTIVE: Determine the relation of xanthine oxidase (XO) activity and the outcome of
septic patients and its relation to oxidative damage and clinical parameters of sepsis …

Enhanced expression and activity of xanthine oxidoreductase in the failing heart

JW de Jong, RG Schoemaker, R de Jonge… - Journal of Molecular and …, 2000 - Elsevier
The molecular basis for heart failure is unknown, but oxidative stress is associated with the
pathogenesis of the disease. We tested the hypothesis that the activity of xanthine …

Determination of xanthine oxidoreductase forms: influence of reaction conditions

R Martı́, E Varela, C Pascual, RM Segura - Clinica chimica acta, 2001 - Elsevier
Xanthine oxidoreductase (XOR) has been implicated in ischaemia-reperfusion injury, and
increases in this enzyme have been found in plasma of patients with different illnesses. The …

[HTML][HTML] Xanthine oxidase inhibitors in elderly patients with heart failure: useful or useless?

V Presta, B Citoni, G Tocci - Internal and Emergency Medicine, 2019 - Springer
Elevated serum uric acid levels have been progressively emerged as a powerful and
independent risk factor for many cardiovascular diseases, including hypertension [1, 2] …

[HTML][HTML] Association between plasma xanthine oxidoreductase activity and in-hospital outcomes in patients with stable coronary artery disease after percutaneous …

R Sato, K Akita, T Ikoma, K Iguchi, T Murase… - Plos one, 2021 - journals.plos.org
Objectives Reactive oxygen species generated by xanthine oxidoreductase (XOR) are
associated with the progression of atherosclerosis. However, changes in plasma XOR …

[PDF][PDF] The relationship between xanthine oxidoreductase and xanthine oxidase activities in plasma and kidney dysfunction

H Terawaki, T Murase, A Nakajima, K Aoyagi… - J Clin Exp …, 2017 - researchmap.jp
Background: Oxidative stress (OS) is thought to play a role in detrimental events among
patients with chronic kidney disease (CKD). Although the mechanism of OS increases in …

Plasma xanthine oxidoreductase activity change over 12 months independently associated with change in serum uric acid level: MedCity21 health examination …

M Kurajoh, S Fukumoto, T Murase… - Clinical Chemistry and …, 2021 - degruyter.com
Plasma xanthine oxidoreductase (XOR) activity assays previously developed are generally
based on the rate of production of uric acid from its substrate xanthine, determined with an …