Background—Oxidative stress may contribute to heart failure (HF) progression. Inhibiting
xanthine oxidase in hyperuricemic HF patients may improve outcomes. Methods and …

Background We developed a novel high-sensitive assay for plasma xanthine
oxidoreductase (XOR) activity that is not affected by the original serum uric acid level …

Introduction. Xanthine oxidoreductase (XOR) is an enzyme belonging to the class of
hydroxylases. XOR is stated, inter alia, in the kidneys, liver, and small intestine as well as in …

The pathophysiologic understanding of chronic heart failure (CHF) has shifted from a mere
hemodynamic disorder to a much more complex approach including changes and …

Myocardial ischemia results from the reduction of coronary flow to such an extent that supply
of oxygen to the myocardium does not meet the oxygen demand of myocardial tissue …

Background Hyperuricemia has a close relationship with cardiovascular diseases including
heart failure. However, it is controversial whether xanthine oxidase inhibition has benefits for …

The role of xanthine oxidase (XOD) in patients undergoing chronic hemodialysis treatment
(HD) is poorly understood. Geriatric nutritional risk index (GNRI)≤ 90 could be linked with …

Reactive oxygen species, in particular superoxide, have been closely linked to the
underlying pathophysiology of ischemic cardiomyopathy: superoxide not only mediates …

Xanthine oxidase inhibition for chronic heart failure: is allopurinol the next therapeutic advance
in heart failure? - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

An investigation was made into the possible involvement of the enzyme xanthine oxidase
(XO)(EC 1.1. 3.22), both reversible (XOrev) and irreversible (XOirr), in damage observed …