Systematic elucidation of the bioactive alkaloids and potential mechanism from Sophora flavescens for the treatment of eczema via network pharmacology

Y Lin, XJ Chen, L He, XL Yan, QR Li, X Zhang… - Journal of …, 2023 - Elsevier
Ethnopharmacology relevance Sophora flavescens is a frequently used traditional Chinese
medicine (TCM) for the treatment of skin disorders, diarrhea, vaginal itching and …

Prediction of the therapeutic mechanism responsible for the effects of Sophora japonica flower buds on contact dermatitis by network-based pharmacological analysis

Y Kim, Y Oh, H Lee, B Yang, CH Choi, H Jeong… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance The flower buds of Sophora japonica L. are a major
traditional medicine in China, Japan, and Korea and are used to stop bleeding and 'cool the …

[HTML][HTML] The active compounds and therapeutic mechanisms of pentaherbs formula for oral and topical treatment of atopic dermatitis based on network pharmacology

M Chu, MSM Tsang, R He, CWK Lam, ZB Quan… - Plants, 2020 - mdpi.com
To examine the molecular targets and therapeutic mechanism of a clinically proven Chinese
medicinal pentaherbs formula (PHF) in atopic dermatitis (AD), we analyzed the active …

Investigation on the mechanism of 2, 3, 4′, 5-Tetrahydroxystilbene 2-oD-glucoside in the treatment of inflammation based on network pharmacology

L Sun, B Wang, T Sun, F Zhou, B Zhu, C Li… - Computers in biology …, 2022 - Elsevier
Background Inflammation is the pathogenesis of various chronic diseases plaguing clinic for
years. Fallopia multiflora (Thunb.) is a traditional Chinese herbal medicine with a long …

Sophora flavescens-Angelica sinensis in the treatment of eczema by inhibiting TLR4/MyD88/NF-κB pathway

P Sun, X Zhao, W Zhao, L Chen, X Liu, Z Zhan… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Sophora flavescens Ait.-Angelica sinensis (Oliv.)
Diels drug pairing (SA) is a transformed drug pairing from Shengui pill, a traditional Chinese …

[HTML][HTML] Molecular mechanism of the anti-inflammatory effects of Sophorae Flavescentis Aiton identified by network pharmacology

N Zhu, J Hou - Scientific reports, 2021 - nature.com
Inflammation, a protective response against infection and injury, involves a variety of
biological processes. Sophorae Flavescentis (Kushen) is a promising Traditional Chinese …

Network Pharmacology‐Based Analysis of the Underlying Mechanism of Hyssopus cuspidatus Boriss. for Antiasthma: A Characteristic Medicinal Material in Xinjiang

R Liu, Y Mao, Z Gu, J He - Evidence‐Based Complementary …, 2021 - Wiley Online Library
Background. Hyssopus cuspidatus Boriss.(Shen Xiang Cao (SXC)), a traditional medicine
herb in Xinjiang, has a long history of being used by minorities to treat asthma. However, its …

Therapeutic effects of Siegesbeckia orientalis L. And its active compound luteolin in rheumatoid arthritis: Network pharmacology, molecular docking and experimental …

B Xiao, J Li, Z Qiao, S Yang, HY Kwan, T Jiang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Rheumatoid arthritis (RA) is a common difficult disease
with a high disability rate. Siegesbeckia orientalis L.(SO), a Chinese medicinal herb that is …

Investigation of the active components and mechanisms of Schisandra chinensis in the treatment of asthma based on a network pharmacology approach and …

X Lv, Z Xu, G Xu, H Li, C Wang, J Chen, J Sun - Food & Function, 2020 - pubs.rsc.org
The aim of this paper was to investigate the active components of Schisandra chinensis in
the treatment of asthma and the related mechanisms by a network pharmacology approach …

[HTML][HTML] An integrative analysis to predict the active compounds and explore polypharmacological mechanisms of Orthosiphon stamineus Benth.

X Wang, W Zhao, X Zhang, Z Wang, C Han, J Xu… - Computers in Biology …, 2023 - Elsevier
Abstract Background Orthosiphon stamineus Benth is a dietary supplement and traditional
Chinese herb with widespread clinical applications, but a comprehensive understanding of …