Background and purpose Biomarker changes in cognitively impaired patients with small
vessel disease are largely unknown. The rate of amyloid/lacune progression, cortical …

We tried to evaluate and to compare usefulness of two brief cognitive tests in early detection
of cognitive decline in subjects with increased cerebrovascular (CV) risk. As CV risk factors …

We conducted a cross-sectional study to characterize the relationship between total and
modified small vessel disease (SVD) score with vascular cognitive impairment (VCI) …

Introduction: The neuropsychological feature of vascular mild cognitive impairment is a
deficit of the frontal-subcortical circuit; however, the features in the early stage are not …

BACKGROUND: Some patients with stroke have prestroke cognitive impairment (pre-SCI),
but its etiology is not clear. The aim of this cross-sectional study was to assess the frequency …

Introduction It remains unknown whether the global small vessel disease (SVD) burden
predicts post‐stroke outcomes. Methods In a prospective multicenter study of 666 ischemic …

Background The effect of amyloid-β (Aβ) on cognitive impairment in patients with small
subcortical infarction remains controversial, although a growing body of evidence shows a …

Cerebral small-vessel disease is common in older people and may contribute to the
development of dementia. The objective of the present study was to evaluate the …

ABSTRACT The recognition of Cerebrovascular Disease (CVD) at earlier clinical stages
may favor the control of vascular risk factors and prevention of dementia. However …

Background: Cross-sectional studies have indicated that subcortical ischemic vascular
disease (SIVD), as defined according to imaging criteria, is associated with a specific clinical …