Intravenous ferric derisomaltose for the treatment of iron deficiency anemia

M Auerbach, D Henry… - American Journal of …, 2021 - Wiley Online Library
Intravenous (IV) iron is the therapy of choice when oral iron is ineffective or poorly tolerated,
yet use has been limited by fears of hypersensitivity reactions (HSRs). Newer formulations …

A randomized trial of iron isomaltoside versus iron sucrose in patients with iron deficiency anemia

R Derman, E Roman, MR Modiano… - American journal of …, 2017 - Wiley Online Library
Iron deficiency anemia (IDA) is common in many chronic diseases, and intravenous (IV) iron
offers a rapid and efficient iron correction. This trial compared the efficacy and safety of iron …

Safety and efficacy of total dose infusion of 1,020 mg of ferumoxytol administered over 15 min

M Auerbach, W Strauss, S Auerbach… - American journal of …, 2013 - Wiley Online Library
For the majority of patients with iron deficiency anemia (IDA), a full course of intravenous (IV)
iron is 1 g. Most IV irons require 5–10 administrations of 100–300 mg. We have successfully …

A multicenter study evaluating the effectiveness and safety of single‐dose low molecular weight iron dextran vs single‐dose ferumoxytol for the treatment of iron …

J Cohen, A Khudanyan, J Lu, J Wing… - American journal of …, 2020 - Wiley Online Library
There are multiple intravenous (IV) iron formulations available, of which several may be
administered as single‐dose infusions such as low‐molecular weight iron dextran (LMWID) …

A prospective, multi‐center, randomized comparison of iron isomaltoside 1000 versus iron sucrose in patients with iron deficiency anemia; the FERWON‐IDA trial

M Auerbach, D Henry, RJ Derman… - American journal of …, 2019 - Wiley Online Library
Iron deficiency anemia (IDA) is prevalent, and intravenous iron, especially if given in a single
dose, may result in better adherence compared with oral iron. The present trial (FERWON …

Efficacy and safety of IV ferumoxytol for adults with iron deficiency anemia previously unresponsive to or unable to tolerate oral iron

S Vadhan‐Raj, W Strauss, D Ford… - American journal of …, 2014 - Wiley Online Library
Although oral iron is the initial treatment approach for iron deficiency anemia (IDA), some
patients fail to respond to or cannot tolerate oral iron. This double‐blind safety and efficacy …

An evaluation of ferric derisomaltose as a treatment for anemia

X Kassianides, R Bodington… - Expert Review of …, 2021 - Taylor & Francis
ABSTRACT Introduction: Originally approved in Europe in 2009, ferric derisomaltose is the
most recently authorized intravenous iron compound in the United States of America (2020) …

A Phase III, randomized, open‐label trial of ferumoxytol compared with iron sucrose for the treatment of iron deficiency anemia in patients with a history of …

D Hetzel, W Strauss, K Bernard, Z Li… - American journal of …, 2014 - Wiley Online Library
Iron deficiency anemia (IDA) is the most common form of anemia worldwide. Although oral
iron is used as first‐line treatment, many patients are unresponsive to or cannot take oral …

Safety Profile of Iron Carboxymaltose, a New High Dose Intravenous Iron in Patients with Iron Deficiency Anemia.

MH Seid, A Mangione, TG Valaoras, LB Anthony… - Blood, 2006 - Elsevier
Currently available IV iron agents pose substantial safety and practical challenges to
effective management of iron deficiency anemia. Iron dextran administration requires a test …

[PDF][PDF] Safety and efficacy of rapidly administered (one hour) one gram of low molecular weight iron dextran (INFeD) for the treatment of iron deficient anemia

M Auerbach, JA Pappadakis, H Bahrain… - American journal of …, 2011 - academia.edu
Oral iron is a standard treatment of iron deficient anemia despite high rates of intolerance
and nonadherence and may not replenish iron stores rapidly enough to meet ongoing …