Objective To investigate structural and functional neural organization in amyotrophic lateral
sclerosis (ALS), primary lateral sclerosis (PLS), and progressive muscular atrophy (PMA) …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by
progressive loss of motor function. While the pathogenesis of ALS remains largely unknown …

Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease selectively
affecting upper and lower motor neurons. Patients with ALS suffer from progressive paralysis …

Neuroimaging studies of patients with amyotrophic lateral sclerosis (ALS) have shown
widespread alterations in structure, function, and connectivity in both motor and non-motor …

Background Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive
neurodegenerative disorder. Diffusion magnetic resonance imagining (MRI) studies have …

Amyotrophic lateral sclerosis (ALS) is a rare degenerative disorder characterized by loss of
upper and lower motor neurons. Neuroimaging has provided noticeable evidence that ALS …

Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease
characterised by motor neuron degeneration. How this disease affects the central motor …

Abstract Amyotrophic Lateral Sclerosis (ALS) is one of the most severe neurodegenerative
diseases, which is known to affect upper and lower motor neurons. In contrast to the …

Background and purpose The present study utilized a multimodal approach encompassing
connectome networks combined with brain volume analysis, and assessment of cortical …

Background Half of all amyotrophic lateral sclerosis-frontotemporal spectrum disorder (ALS-
FTSD) patients are classified as cognitively impaired, of which 10% have frontotemporal …