Topical drug delivery against cutaneous leishmaniasis (CL) signifies an effective alternate
for improving the availability and reducing the toxicity associated with the parenteral …

Abstract Glimepiride (3rd-generation sulfonylurea) is used for treatment of type 2 diabetes,
but its oral administration has been associated with severe gastric disturbances such as …

Tazarotene (TAZ) is a topical synthetic retinoid used in psoriasis treatment, however, it is
extremely lipophilic and exhibits skin irritation. Research is in a state of continuous …

Niosomes are novel carriers that show superior transdermal permeation enhancement but
require the addition of charged stabilizers. In this study, niosomes were prepared using …

Felodipine is a dihydropyridine calcium channel blocker commonly used for the treatment of
mild to moderate hypertension and angina pectoris. Felodipine undergoes extensive hepatic …

Span 40-based niosomes were employed as nanocarriers to improve cutaneous absorption
of salidroside. The niosomal formulation with a molar proportion of Span 40 to cholesterol of …

Non-invasive and non-toxic drugs are highly needed for the treatment of several skin
diseases. Among those, local topical treatment is more desirable over oral treatment that …

The aim of this study was to develop different vesicular systems for sertaconazole nitrate and
evaluate the ability of targeting deep skin layers to treat dermal fungal infection. Therefore …

New generation of amphiphilic vesicles known as aspasomes were investigated as potential
carriers for transdermal delivery of tizanidine (TZN). Using full factorial design, an optimal …

Context: Transdermal formulations contain permeation enhancer which causes skin
damage. Ceramide 2 is natural lipid found in stratum corneum (SC). Objective: Drug-loaded …