Inhaled nitric oxide (iNO) has many extrapulmonary effects. As the half-life of nitric oxide
(NO) in blood is orders of magnitude less than the circulation time from lungs to the brain …

The role of nitric oxide, a compound involved in neurotransmission and regulation of
cerebral blood flow, in cerebral ischemia is still not fully elucidated yet. Although well studied …

The role of the neural messenger nitric oxide (NO) in cerebral ischaemia has been
investigated extensively in the past decade. NO may play either a protective or destructive …

Nitric oxide (NO) is a unique biological messenger molecule which mediates diverse
physiologic roles. NO mediates blood vessel relaxation by endothelium, immune activity of …

Roles proposed for nitric oxide (NO) in CNS pathophysiology are increasingly diverse and
range from intercellular signaling, through necrotic killing of cells and invading pathogens, to …

Nitric oxide (NO) is a diffusible regulatory molecule involved in a wide range of physiological
and pathological events. At the tissue level, a local and temporary increase in NO …

The pivotal discovery that nitric oxide was a key signaling molecule in the cardiovascular
system resulted in the awarding of the Nobel prize in 1998 to the persons who discovered its …

This review focuses on the effects that ischemia and hypoxia have on the cerebral cortex
and the cerebellum during different periods of life. The acute interruption or reduction of …

Ventilation with nitric oxide (NO) is increasingly being used to treat pulmonary hypertension
in the newborn. In the brain, NO has vasoactive properties and is involved in …

Previous studies have shown that brain tissue hypoxia results in increased N-methyl-D-
aspartate (NMDA) receptor activation and receptor-mediated increase in intracellular …