Inhaled nitric oxide in term and near-term infants: neurodevelopmental follow-up of the neonatal inhaled nitric oxide study group (NINOS)

Neonatal Inhaled Nitric Oxide Study Group - The Journal of pediatrics, 2000 - Elsevier
Background: Inhaled nitric oxide (INO) improved oxygenation and reduced the occurrence of
death or extracorporeal membrane oxygenation in term and near-term hypoxic neonates …

Impact of inhaled nitric oxide on white matter damage in growth-restricted neonatal rats

H Pham, AP Duy, J Pansiot, B Bollen, J Gallego… - Pediatric …, 2015 - nature.com
Background: Fetal growth restriction is the second leading cause of perinatal morbidity and
mortality, and neonates with intrauterine growth retardation (IUGR) have increased …

The interplay of nitric oxide and peroxynitrite with signal transduction pathways: implications for disease

J McAndrew, RP Patel, H Jo, T Cornwell, T Lincoln… - Seminars in …, 1997 - Elsevier
Since the discovery that at least one form of endothelium derived relaxing factor is nitric
oxide (NO), numerous studies have uncovered diverse roles for this free radical in a variety …

Nitric oxide in health and disease of the nervous system

AB Knott, E Bossy-Wetzel - Antioxidants & redox signaling, 2009 - liebertpub.com
Nitric oxide (NO) is an important messenger molecule in a variety of physiological systems.
NO, a gas, is produced from L-arginine by different isoforms of nitric oxide synthase (NOS) …

Dual role of nitric oxide in adult neurogenesis

A Cárdenas, MA Moro, O Hurtado, JC Leza… - Brain research …, 2005 - Elsevier
In the last decade, it has been demonstrated that neurogenesis persists in the adult
mammalian brain and that it is induced after insults, where newborn neurons migrate to …

Increased neurons containing neuronal nitric oxide synthase in the brain of a hypoxic-ischemic neonatal rat model

Y Higuchi, H Hattori, R Hattori, K Furusho - Brain and Development, 1996 - Elsevier
We evaluated the temporal profile of the number of neurons containing neuronal nitric oxide
synthase (nNOS neurons) in the brain of a neonatal hypoxic-ischemic rat model. Hypoxic …

Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures

VL Dawson, TM Dawson, DA Bartley… - Journal of …, 1993 - Soc Neuroscience
In addition to mediating several physiological functions, nitric oxide (NO) has been
implicated in the cytotoxicities observed following activation of macrophages or excess …

Prolonged suppression of brain nitric oxide synthase activity by 7-nitroindazole protects against cerebral hypoxic–ischemic injury in neonatal rat

A Ishida, WH Trescher, MS Lange, MV Johnston - Brain and Development, 2001 - Elsevier
Nitric oxide mediates glutamate-induced excitotoxicity associated with cerebral hypoxia–
ischemia through production in the brain by several isoforms of nitric oxide synthase (NOS) …

Nitric oxide in the central nervous system

SA Lipton, DJ Singel, JS Stamler - Progress in brain research, 1994 - Elsevier
Publisher Summary In the central nemous system (CNS), nitric oxide (NO) or closely related
molecules have been reported to be both neurodestructive and neuroprotective. This …

Cerebral blood flow regulation by nitric oxide in neurological disorders

N Toda, K Ayajiki, T Okamura - Canadian journal of physiology …, 2009 - cdnsciencepub.com
There has been a rapid increase in the amount of information on the physiological and
pathophysiological roles of nitric oxide (NO) in the brain. This molecule, which is formed by …