Low baseline neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict increased overall survival in locally recurrent rectal cancer despite R1 margins

E Daveri, L Sorrentino, L Lalli, M Guaglio… - Digestive and Liver …, 2022 - Elsevier
Background Prognostic features in locally recurrent rectal cancer (LRRC), beyond R0
surgery, are unknown. Aims Aim of the present study was to evaluate the prognostic role of …

Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic factors in locally advanced rectal cancer

V Duque-Santana, F López-Campos, M Martin-Martin… - Oncology, 2023 - karger.com
Introduction: The standard therapy for locally advanced rectal cancer (LARC) is based on
neoadjuvant chemoradiotherapy (nCRT) with fluoropyrimidines. There are different …

Prognostic impact of neutrophil-to-lymphocyte ratio in patients with advanced low rectal cancer treated with preoperative chemoradiotherapy

T Nagasaki, T Akiyoshi, Y Fujimoto, T Konishi… - Digestive surgery, 2015 - karger.com
Background: The neutrophil-to-lymphocyte ratio (NLR) is considered an indicator of systemic
inflammation and may predict prognosis in colorectal cancer. In this study, we examined the …

[HTML][HTML] The pre-treatment platelet-to-lymphocyte ratio as a prognostic factor for loco-regional control in locally advanced rectal cancer

R Partl, K Paal, B Stranz, E Hassler, M Magyar… - Diagnostics, 2023 - mdpi.com
Chronic inflammatory reactions have been proven to represent relevant mechanisms for the
development and progression of cancer in numerous tumor entities. There is evidence that …

[HTML][HTML] Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as predictive and prognostic markers in patients with locally advanced rectal cancer treated with …

S Dudani, H Marginean, PA Tang, JG Monzon… - BMC cancer, 2019 - Springer
Background A standard therapy for locally advanced rectal cancer (LARC) includes
fluoropyrimidine (FP)-based neoadjuvant chemoradiation (nCRT). Previous studies have …

[HTML][HTML] Baseline neutrophil-lymphocyte ratio (≥ 2.8) as a prognostic factor for patients with locally advanced rectal cancer undergoing neoadjuvant chemoradiation

L Shen, H Zhang, L Liang, G Li, M Fan, Y Wu, J Zhu… - Radiation …, 2014 - Springer
Background The neutrophil-lymphocyte ratio (NLR) has been proposed as an indicator of
systemic inflammatory response and may predict the clinical outcome in some cancers, such …

[HTML][HTML] Prognostic impact of persistent lower neutrophil-to-lymphocyte ratio during preoperative chemoradiotherapy in locally advanced rectal cancer patients: A …

YJ Cha, EJ Park, SH Baik, KY Lee, J Kang - PLoS One, 2019 - journals.plos.org
Purpose This study investigated the significance of change in neutrophil-to-lymphocyte ratio
(NLR) during preoperative chemoradiotherapy (preop-CRT) in patients with non-metastatic …

[HTML][HTML] Assessment of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and platelet count as predictors of long-term outcome after R0 resection for …

C Pedrazzani, G Mantovani, E Fernandes, F Bagante… - Scientific reports, 2017 - nature.com
Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and platelet count
(PC) were shown to be prognostic in several solid malignancies. We analysed 603 R0 …

Prognostic and predictive value of neutrophil-to-lymphocyte ratio after curative rectal cancer resection: a systematic review and meta-analysis

HKS Hamid, GN Davis, M Trejo-Avila, PO Igwe… - Surgical Oncology, 2021 - Elsevier
Background Neutrophil-to-lymphocyte ratio (NLR) has been shown to be associated with
poor prognosis in numerous solid malignancies. Here, we quantify the prognostic value of …

[HTML][HTML] Association of neutrophil-to-lymphocyte ratio, radiotherapy fractionation/technique, and risk of development of distant metastasis among patients with locally …

G Yang, JS Chang, JE Choi, ES Baek, SS Kim… - Radiation …, 2022 - Springer
Background We investigated the prognostic impact of the neutrophil-to-lymphocyte ratio
(NLR) in patients with locally advanced rectal cancer (LARC) and whether modifiable factors …