Objective Research in animals has shown that chronic stress exacerbates tau pathology. In
humans, psychological stress has been associated with higher risk of Alzheimer disease …

Stressful life experiences are likely etiological factors in sporadic forms of Alzheimer's
disease (AD). Many AD patients hypersecrete glucocorticoids (GCs), and their GC levels …

Mechanisms of resilience against tau pathology in individuals across the Alzheimer's
disease spectrum are insufficiently understood. Longitudinal data are necessary to reveal …

Personality traits such as Neuroticism and Conscientiousness are associated with Alzheimer
disease (AD) pathophysiology in cognitively normal (CN) and impaired individuals, and may …

Background: African Americans (AA) have a higher Alzheimer's disease (AD) prevalence
and report more perceived stress than White Americans. The biological basis of the stress …

Importance Better understanding is needed of the degree to which individuals tolerate
Alzheimer disease (AD)–like pathological tau with respect to brain structure (brain …

Background: The pathophysiological process of amyloid-, tau deposition, and
neurodegeneration of Alzheimer's disease (AD) begin in a preclinical phase, while anxiety is …

Objective Despite advances toward understanding the etiology of Alzheimer's disease (AD),
it remains unclear which aspects of this disease are affected by environmental factors …

Depression and related neurobehavioral symptoms are common features of Alzheimer's
disease and other dementias. The presence of these potentially modifiable neurobehavioral …

Memory impairment in Alzheimer's disease patients is thought to be associated with the
accumulation of amyloid-beta peptides and tau proteins. However, inconsistent reports of …