Particulate matter toxicity is Nrf2 and mitochondria dependent: the roles of metals and polycyclic aromatic hydrocarbons
M Pardo, X Qiu, R Zimmermann… - Chemical research in …, 2020 - ACS Publications
Particulate matter (PM), an important component of air pollution, induces significant adverse
health effects. Many of the observed health effects caused by inhaled PM are associated …
health effects. Many of the observed health effects caused by inhaled PM are associated …
Nrf2 protects against diverse PM2. 5 components-induced mitochondrial oxidative damage in lung cells
Nrf2 is an important transcription factor implicated in the oxidative stress response, which
has been reported to play an important role in the way by which air pollution particulate …
has been reported to play an important role in the way by which air pollution particulate …
In vivo and in vitro evidence for the involvement of Nrf2-antioxidant response element signaling pathway in the inflammation and oxidative stress induced by …
Environmental pollution is one of the risk factors for respiratory diseases. The nuclear factor
erythroid 2-related factor 2 (Nrf2) is the major mechanisms contributing to cellular defense …
erythroid 2-related factor 2 (Nrf2) is the major mechanisms contributing to cellular defense …
Air particulate matter induced oxidative stress and inflammation in cardiovascular disease and atherosclerosis: The role of Nrf2 and AhR-mediated pathways
AO Lawal - Toxicology letters, 2017 - Elsevier
Air particulate matter (PM) is an important component of air pollution, which has been
reported to play important role in the adverse health effects of the latter. Extensive …
reported to play important role in the adverse health effects of the latter. Extensive …
Long-term exposure to PM2. 5 aggravates pulmonary fibrosis and acute lung injury by disrupting Nrf2-mediated antioxidant function
Epidemiological studies have indicated that exposure to ambient air-borne fine particulate
matter (PM2. 5) is associated with many cardiopulmonary diseases; however, the underlying …
matter (PM2. 5) is associated with many cardiopulmonary diseases; however, the underlying …
Particulate matter induces tissue oxinflammation: from mechanism to damage
G Valacchi, N Magnani, B Woodby… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Oxidative stress and oxidative damage are central hypothetical mechanisms
for the adverse effects of airborne particulate matter (PM). Activation of inflammatory cells …
for the adverse effects of airborne particulate matter (PM). Activation of inflammatory cells …
Relationship between redox activity and chemical speciation of size-fractionated particulate matter
L Ntziachristos, JR Froines, AK Cho… - Particle and fibre toxicology, 2007 - Springer
Background Although the mechanisms of airborne particulate matter (PM) related health
effects remain incompletely understood, one emerging hypothesis is that these adverse …
effects remain incompletely understood, one emerging hypothesis is that these adverse …
Mitochondrial alterations triggered by repeated exposure to fine (PM2. 5-0.18) and quasi-ultrafine (PM0. 18) fractions of ambient particulate matter
J Sotty, J Kluza, C De Sousa, M Tardivel… - Environment …, 2020 - Elsevier
Nowadays ambient particulate matter (PM) levels still regularly exceed the guideline values
established by World Health Organization in most urban areas. Numerous experimental …
established by World Health Organization in most urban areas. Numerous experimental …
Composition of air pollution particles and oxidative stress in cells, tissues, and living systems
AJ Ghio, MS Carraway, MC Madden - Journal of Toxicology and …, 2012 - Taylor & Francis
Epidemiological studies demonstrated an association between increased levels of ambient
air pollution particles and human morbidity and mortality. Production of oxidants, either …
air pollution particles and human morbidity and mortality. Production of oxidants, either …
[HTML][HTML] Redox toxicology of environmental chemicals causing oxidative stress
F Zheng, FM Gonçalves, Y Abiko, H Li, Y Kumagai… - Redox biology, 2020 - Elsevier
Living organisms are surrounded with heavy metals such as methylmercury, manganese,
cobalt, cadmium, arsenic, as well as pesticides such as deltamethrin and paraquat, or …
cobalt, cadmium, arsenic, as well as pesticides such as deltamethrin and paraquat, or …