Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats

M Crumeyrolle-Arias, M Jaglin, A Bruneau… - …, 2014 - Elsevier
Background and aims Establishment of the gut microbiota is one of the most important
events in early life and emerging evidence indicates that the gut microbiota influences …

[HTML][HTML] Microbiota modulate anxiety-like behavior and endocrine abnormalities in hypothalamic-pituitary-adrenal axis

R Huo, B Zeng, L Zeng, K Cheng, B Li, Y Luo… - Frontiers in Cellular …, 2017 - frontiersin.org
Intestinal microbes are an important system in the human body, with significant effects on
behavior. An increasing body of research indicates that intestinal microbes affect brain …

[HTML][HTML] Brain neurotransmitter modulation by gut microbiota in anxiety and depression

F Huang, X Wu - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Anxiety and depression are highly prevalent mental illnesses worldwide and have long
been thought to be closely associated to neurotransmitter modulation. There is growing …

Gut microbiota regulates mouse behaviors through glucocorticoid receptor pathway genes in the hippocampus

Y Luo, B Zeng, LI Zeng, X Du, B Li, R Huo, L Liu… - Translational …, 2018 - nature.com
Gut microbiota has an important role in the immune system, metabolism, and digestion, and
has a significant effect on the nervous system. Recent studies have revealed that abnormal …

Reduced anxiety‐like behavior and central neurochemical change in germ‐free mice

KM Neufeld, N Kang, J Bienenstock… - …, 2011 - Wiley Online Library
Background There is increasing interest in the gut‐brain axis and the role intestinal
microbiota may play in communication between these two systems. Acquisition of intestinal …

Interactions between gut microbiota and acute restraint stress in peripheral structures of the hypothalamic–pituitary–adrenal axis and the intestine of male mice

K Vagnerová, M Vodička, P Hermanová… - Frontiers in …, 2019 - frontiersin.org
The gut microbiota play an important role in shaping brain functions and behavior, including
the activity of the hypothalamus-pituitary-adrenocortical (HPA) axis. However, little is known …

Gut–brain axis: how the microbiome influences anxiety and depression

JA Foster, KAMV Neufeld - Trends in neurosciences, 2013 - cell.com
Within the first few days of life, humans are colonized by commensal intestinal microbiota.
Here, we review recent findings showing that microbiota are important in normal healthy …

Effects of microbiota transplantation and the role of the vagus nerve in gut–brain axis in animals subjected to chronic mild stress

PRM Ávila, M Fiorot, M Michels, D Dominguini… - Journal of affective …, 2020 - Elsevier
Introduction Currently, there is a growing emphasis on the study of intestinal signaling as an
influencer in the pathophysiology of neuropsychiatric diseases, and the gut–brain axis is …

The gut microbiome modulates the changes in liver metabolism and in inflammatory processes in the brain of chronic unpredictable mild stress rats

W Lv, X Wu, W Chen, Y Li, G Zhang… - Oxidative Medicine …, 2019 - Wiley Online Library
Generally, depression is the result of complex gene‐environment interactions. Recent
studies have showed that the gut microbiota can affect brain function through the microbiota …

Fecal microbiota transplantation ameliorates stress-induced depression-like behaviors associated with the inhibition of glial and NLRP3 inflammasome in rat brain

J Rao, Y Qiao, R Xie, L Lin, J Jiang, C Wang… - Journal of Psychiatric …, 2021 - Elsevier
Background Evidence from previous studies has demonstrated that the gut-microbiota-brain
axis is vital in regulating of behavior and neuroinflammation in the central nervous system …