Gut/brain axis and the microbiota

EA Mayer, K Tillisch, A Gupta - The Journal of clinical …, 2015 - Am Soc Clin Investig
Tremendous progress has been made in characterizing the bidirectional interactions
between the central nervous system, the enteric nervous system, and the gastrointestinal …

Stress and antibiotics alter luminal and wall‐adhered microbiota and enhance the local expression of visceral sensory‐related systems in mice

M Aguilera, P Vergara… - Neurogastroenterology & …, 2013 - Wiley Online Library
Background Stress leads to altered gastrointestinal neuro‐immune responses. We
characterized the interaction between stress and gut commensal microbiota and their role …

Combined probiotics attenuate chronic unpredictable mild stress-induced depressive-like and anxiety-like behaviors in rats

L Huang, X Lv, X Ze, Z Ma, X Zhang, R He… - Frontiers in …, 2022 - frontiersin.org
Increasing evidence indicated that probiotics can be effective in improving behaviors similar
to depression and anxiety disorders. However, the underlying mechanisms remain unclear …

[HTML][HTML] Strain specific stress-modulating effects of candidate probiotics: A systematic screening in a mouse model of chronic restraint stress

LK Stenman, E Patterson, J Meunier, FJ Roman… - Behavioural Brain …, 2020 - Elsevier
Background Changes in the gut microbiota have been implicated in mood and cognition. In
rodents, supplementation with certain bacteria have been shown to alleviate adverse effects …

[HTML][HTML] The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders

K Socała, U Doboszewska, A Szopa, A Serefko… - Pharmacological …, 2021 - Elsevier
Emerging evidence indicates that the gut microbiota play a crucial role in the bidirectional
communication between the gut and the brain suggesting that the gut microbes may shape …

[HTML][HTML] Decoding the neurocircuitry of gut feelings: Region-specific microbiome-mediated brain alterations

BL Sharvin, MR Aburto, JF Cryan - Neurobiology of Disease, 2023 - Elsevier
Research in the last decade has unveiled a crucial role for the trillions of microorganisms
that reside in the gut in influencing host neurodevelopment across the lifespan via the …

Sex-specific modulation of the gut microbiome and behavior in Siberian hamsters

KE Sylvia, CP Jewell, NM Rendon, EAS John… - Brain, Behavior, and …, 2017 - Elsevier
The gut microbiome is a diverse, host-specific, and symbiotic bacterial environment that is
critical for mammalian survival and exerts a surprising yet powerful influence on brain and …

Gender-based differences in host behavior and gut microbiota composition in response to high fat diet and stress in a mouse model

LC Bridgewater, C Zhang, Y Wu, W Hu, Q Zhang… - Scientific reports, 2017 - nature.com
Obesity is associated with a high prevalence of mood disorders such as anxiety and
depression. Both stress and high fat diet can alter the gut microbiota and contribute to …

Growing up in a bubble: using germ-free animals to assess the influence of the gut microbiota on brain and behavior

P Luczynski, KA McVey Neufeld… - International Journal …, 2016 - academic.oup.com
There is a growing recognition of the importance of the commensal intestinal microbiota in
the development and later function of the central nervous system. Research using germ-free …

Faecalibacterium prausnitzii (ATCC 27766) has preventive and therapeutic effects on chronic unpredictable mild stress-induced depression-like and anxiety-like …

Z Hao, W Wang, R Guo, H Liu - Psychoneuroendocrinology, 2019 - Elsevier
The realization that the microbiota-gut-brain axis plays a critical role in health and disease,
including neuropsychiatric disorders, is rapidly advancing. An abundance of preclinical …