Stress-induced disturbances along the gut microbiota-immune-brain axis and implications for mental health: Does sex matter?

MC Audet - Frontiers in neuroendocrinology, 2019 - Elsevier
Women are roughly twice as likely as men to suffer from stress-related disorders, especially
major depression and generalized anxiety. Accumulating evidence suggest that microbes …

The microbiota-gut-brain axis in neuropsychiatric disorders: pathophysiological mechanisms and novel treatments

YK Kim, C Shin - Current neuropharmacology, 2018 - ingentaconnect.com
Background: The human gut microbiome comprise a huge number of microorganisms with
co-evolutionary associations with humans. It has been repeatedly revealed that bidirectional …

Effects of 'healthy'fecal microbiota transplantation against the deterioration of depression in fawn-hooded rats

B Hu, P Das, X Lv, M Shi, J Aa, K Wang, L Duan… - Msystems, 2022 - Am Soc Microbiol
Depression is a recurrent, heterogeneous mood disorder occurring in more than 260 million
people worldwide. Gut microbiome dysbiosis is associated with the development of …

Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats

SM O'mahony, VD Felice, K Nally, HM Savignac… - Neuroscience, 2014 - Elsevier
Disruption of bacterial colonization during the early postnatal period is increasingly being
linked to adverse health outcomes. Indeed, there is a growing appreciation that the gut …

Gut microbiota regulates key modulators of social behavior

A Parashar, M Udayabanu - European Neuropsychopharmacology, 2016 - Elsevier
Social behavior plays a pivotal role in the mental well-being of an individual. Continuous
efforts in the past have led to advancements in the area of how the brain regulates emotion …

Regulation of the stress response by the gut microbiota: implications for psychoneuroendocrinology

TG Dinan, JF Cryan - Psychoneuroendocrinology, 2012 - Elsevier
There is now an expanding volume of evidence to support the view that commensal
organisms within the gut play a role in early programming and later responsivity of the stress …

[HTML][HTML] Probiotic consumption relieved human stress and anxiety symptoms possibly via modulating the neuroactive potential of the gut microbiota

T Ma, H Jin, LY Kwok, Z Sun, MT Liong, H Zhang - Neurobiology of Stress, 2021 - Elsevier
Stress has been shown to disturb the balance of human intestinal microbiota and
subsequently causes mental health problems like anxiety and depression. Our previous …

Role of brain-gut-microbiota axis in depression: emerging therapeutic avenues

S Bhatt, J Kanoujia, S Mohana Lakshmi… - CNS & Neurological …, 2023 - ingentaconnect.com
The human gut microbiota plays a significant role in the pathophysiology of central nervous
system-related diseases. Recent studies suggest correlations between the altered gut …

The prebiotics 3′ Sialyllactose and 6′ Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: Evidence for effects on the …

AJ Tarr, JD Galley, SE Fisher, M Chichlowski… - Brain, behavior, and …, 2015 - Elsevier
There are extensive bidirectional interactions between the gut microbiota and the central
nervous system (CNS), and studies demonstrate that stressor exposure significantly alters …

Impact of prebiotics on metabolic and behavioral alterations in a mouse model of metabolic syndrome

LF De Cossio, C Fourrier, J Sauvant, A Everard… - Brain, behavior, and …, 2017 - Elsevier
Mounting evidence shows that the gut microbiota, an important player within the gut-brain
communication axis, can affect metabolism, inflammation, brain function and behavior …