Biocompatibility studies of intravenously administered ionic-crosslinked chitosan-BSA nanoparticles as vehicles for antitumour drugs

N Montero, E Pérez, M Benito, C Teijon… - International Journal of …, 2019 - Elsevier
In this study, a new alternative of ionic crosslinked nanoparticles (NPs) based on chitosan
(C) and bovine serum albumin (A; BSA) was evaluated as drug delivery system for …

Effect of thymoquinone-loaded lipid–polymer nanoparticles as an oral delivery system on anticancer efficiency of doxorubicin

FA Moghaddam, M Ebrahimian, F Oroojalian… - Journal of nanostructure …, 2021 - Springer
In this study, thymoquinone (TQ) was encapsulated into lipid–polymer nanoparticles
(LPNPs) consisting of phosphatidylcholine (PC) and poly lactide–co-glycolide (PLGA) to …

Direct comparison of two albumin-based paclitaxel-loaded nanoparticle formulations: is the crosslinked version more advantageous?

C Li, Y Li, Y Gao, N Wei, X Zhao, C Wang, Y Li… - International journal of …, 2014 - Elsevier
Nanoparticles using albumin as particle matrix have entered the mainstream of drug
delivery. It was reported that non-crosslinked albumin nanoparticles were unstable in …

Biotin-conjugated block copolymeric nanoparticles as tumor-targeted drug delivery systems

SY Kim, SH Cho, YM Lee, LY Chu - Macromolecular Research, 2007 - Springer
To achieve targeted drug delivery for chemotherapy, a ligand-mediated nanoparticulate
drug carrier was designed, which could identify a specific receptor on the surfaces of tumor …

Photo-crosslinked hyaluronic acid nanoparticles with improved stability for in vivo tumor-targeted drug delivery

HY Yoon, H Koo, KY Choi, IC Kwon, K Choi, JH Park… - Biomaterials, 2013 - Elsevier
One of the major hurdles of the nanoparticles as drug carriers is the unintended burst
release of loaded drugs during blood circulation. To surmount this issue, we developed …

Preparation of polyelectrolyte complex nanoparticles of chitosan and poly (2-acry1amido-2-methylpropanesulfonic acid) for doxorubicin release

L Zhang, J Wang, C Ni, Y Zhang, G Shi - Materials Science and …, 2016 - Elsevier
A new kind of polyelectrolyte complex (PEC) based on cationic chitosan (CS) and anionic
poly (2-acry1amido-2-methylpropanesulfonic acid)(PAMPS) was prepared using a polymer …

Chitosan–hyaluronic acid nanoparticles for active targeting in cancer therapy

LE Puluhulawa, IM Joni, KM Elamin, AFA Mohammed… - Polymers, 2022 - mdpi.com
Cancer is the most common cause of death worldwide; therefore, there is a need to discover
novel treatment modalities to combat it. One of the cancer treatments is nanoparticle …

Hyaluronidase enzyme core-5-fluorouracil-loaded chitosan-PEG-gelatin polymer nanocomposites as targeted and controlled drug delivery vehicles

M Rajan, V Raj, AA Al-Arfaj, AM Murugan - International journal of …, 2013 - Elsevier
This study examines the performance of novel hyaluronidase enzyme core-5-fluorouracil-
loaded chitosan-polyethylene glycol-gelatin polymer nanocomposites, which were prepared …

Self-assembled hyaluronic acid nanoparticles as a potential drug carrier for cancer therapy: synthesis, characterization, and in vivo biodistribution

KY Choi, KH Min, JH Na, K Choi, K Kim… - Journal of Materials …, 2009 - pubs.rsc.org
To develop a nano-sized drug delivery system for cancer therapy, amphiphilic hyaluronic
acid conjugates were synthesized by chemical conjugation of hydrophobic 5β-cholanic acid …

Formation of positively charged poly (butyl cyanoacrylate) nanoparticles stabilized with chitosan

SC Yang, HX Ge, Y Hu, XQ Jiang, CZ Yang - Colloid and Polymer Science, 2000 - Springer
To investigate the formation of positively charged nanoparticles (NP) stabilized with
chitosan, positively charged poly (butyl cyanoacrylate)(PBCA) NP were prepared by …