Carbapenemases: Transforming Acinetobacter baumannii into a Yet More Dangerous Menace

MS Ramirez, RA Bonomo, ME Tolmasky - Biomolecules, 2020 - mdpi.com
Acinetobacter baumannii is a common cause of serious nosocomial infections. Although
community-acquired infections are observed, the vast majority occur in people with …

Acinetobacter baumannii: biology and drug resistance—role of carbapenemases

P Nowak, P Paluchowska - Folia histochemica et …, 2016 - journals.viamedica.pl
Acinetobacter baumannii is a Gram-negative, glucose-non-fermenting, oxidase-negative
coccobacillus, most commonly associated with the hospital settings. The ability to survive in …

Carbapenem resistance in Acinetobacter baumannii: laboratory challenges, mechanistic insights and therapeutic strategies

I Abbott, GM Cerqueira, S Bhuiyan… - Expert review of anti …, 2013 - Taylor & Francis
Unprecedented levels of antimicrobial resistance in bacterial isolates have prompted great
concerns globally. In 2012 the WHO released a publication outlining the evolving threat of …

Carbapenem resistance in Acinetobacter baumannii, and their importance in hospital‐acquired infections: a scientific review

M Nguyen, SG Joshi - Journal of applied microbiology, 2021 - academic.oup.com
Carbapenem is an important therapy for serious hospital‐acquired infections and for the
care of patients affected by multidrug‐resistant organisms, specifically Acinetobacter …

[HTML][HTML] Carbapenemases in Acinetobacter baumannii. Review of their dissemination in Latin America

CH Rodríguez, M Nastro, A Famiglietti - Revista argentina de microbiología, 2018 - Elsevier
Carbapenem resistance in gram-negative bacteria by production of carbapenemases is one
of the most challenging issues regarding healthcare worldwide. We review the epidemiology …

OXA-type carbapenemases in Acinetobacter baumannii in South America

A Opazo, M Domínguez, H Bello, SGB Amyes… - The Journal of Infection …, 2012 - jidc.org
Acinetobacter baumannii is an opportunistic pathogen that is frequently involved in
outbreaks of infection, occurring mostly in intensive care units. The increasing incidence of …

Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii with Special Reference to Carbapenemases: A Systematic Review

N Gupta, K Angadi, S Jadhav - Infection and Drug Resistance, 2022 - Taylor & Francis
Carbapenemases are β-lactamase enzymes that hydrolyze a variety of β-lactams including
carbapenem and belong to different Ambler classes (A, B, D). These enzymes can be …

[HTML][HTML] Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology

L Poirel, P Nordmann - Clinical Microbiology and Infection, 2006 - Elsevier
The increasing trend of carbapenem resistance in Acinetobacter baumannii worldwide is a
concern since it limits drastically the range of therapeutic alternatives. Metallo-β-lactamases …

[HTML][HTML] Characterisation of OXA-51, a novel class D carbapenemase found in genetically unrelated clinical strains of Acinetobacter baumannii from Argentina

S Brown, HK Young, SGB Amyes - Clinical microbiology and infection, 2005 - Elsevier
Acinetobacter baumannii is now one of the most frequently encountered nosocomial
pathogens in intensive therapy units, and is renowned for being difficult to treat because of …

[HTML][HTML] Emerging carbapenemases in Gram-negative aerobes

P Nordmann, L Poirel - Clinical Microbiology and Infection, 2002 - Elsevier
Carbapenemases may be defined as β-lactamases that significantly hydrolyze at least
imipenem or/and meropenem. Carbapenemases involved in acquired resistance are of …