Efficacy and safety of paclitaxel combined with cetuximab for head and neck squamous cell carcinoma

T Okada, I Okamoto, H Sato, T Ito, K Miyake… - in vivo, 2021 - iv.iiarjournals.org
Background/Aim: For recurrent/metastatic squamous cell carcinoma of the head and neck
(R/M SCCHN), popular regimens containing platinum-based anticancer agents and immune …

[HTML][HTML] Real-world data of paclitaxel and cetuximab in recurrent/metastatic squamous cell carcinoma of the head and neck

S Aguin, A Carral, L Iglesias, C Pena… - Cancer Diagnosis & …, 2023 - ncbi.nlm.nih.gov
Background/Aim: Prior immune-checkpoint inhibitors, weekly paclitaxel-cetuximab was one
of the few options for platinum-ineligible patients with recurrent/metastatic squamous cell …

Phase II study of combination cetuximab and weekly paclitaxel in patients with metastatic/recurrent squamous cell carcinoma of head and neck (SCCHN): Spanish …

R Hitt, A Irigoyen, J Nuñez, J Grau… - Journal of Clinical …, 2007 - ascopubs.org
6012 Background: Cetuximab and paclitaxel have shown to be active in SCCHN pts and
preclinical data has demonstrated a possible synergy for the combination. In a variety of …

[HTML][HTML] Paclitaxel plus cetuximab as 1st line chemotherapy in platinum-based chemoradiotherapy-refractory patients with squamous cell carcinoma of the head and …

T Enokida, S Okano, T Fujisawa, Y Ueda… - Frontiers in …, 2018 - frontiersin.org
Purpose: We sought to evaluate the efficacy and safety of the combination of cetuximab
(Cmab) and paclitaxel (PTX) in patients with squamous cell carcinoma of the head and neck …

[HTML][HTML] A randomized, phase 2 study of cetuximab plus cisplatin with or without paclitaxel for the first-line treatment of patients with recurrent and/or metastatic …

P Bossi, R Miceli, LD Locati, D Ferrari, S Vecchio… - Annals of …, 2017 - Elsevier
Abstract Background B490 (EudraCT# 2011-002564-24) is a randomized, phase 2b,
noninferiority study investigating the efficacy and safety of first-line cetuximab plus cisplatin …

[HTML][HTML] Randomized phase ii study with cetuximab in combination with 5-FU and cisplatin or carboplatin vs. cetuximab in combination with paclitaxel and carboplatin …

G Tsakonas, L Specht, CA Kristensen, MHC Moreno… - Cancers, 2020 - mdpi.com
Simple Summary The purpose of the CET-MET trial was to find a new platinum-based
chemotherapy regimen in combination with cetuximab for relapsed or metastatic squamous …

Efficacy and safety of weekly paclitaxel combined with cetuximab in the treatment of pretreated recurrent/metastatic head and neck cancer patients

B Jiménez, JM Trigo, BI Pajares, MI Sáez, C Quero… - Oral oncology, 2013 - Elsevier
INTRODUCTION: The addition of cetuximab to weekly paclitaxel has demonstrated high
efficacy in the first-line treatment of patients with recurrent/metastatic squamous cell …

[HTML][HTML] Phase II trial of combination treatment with paclitaxel, carboplatin and cetuximab (PCE) as first-line treatment in patients with recurrent and/or metastatic …

M Tahara, N Kiyota, T Yokota, Y Hasegawa, K Muro… - Annals of …, 2018 - Elsevier
Background The standard of care for first-line treatment of recurrent and/or metastatic
squamous cell carcinoma of the head and neck (R/M SCCHN) is combination treatment with …

Clinical impact of weekly paclitaxel plus cetuximab is comparable to the EXTREME regimen for recurrent/metastatic head and neck squamous cell carcinoma

R Motai, M Sawabe, S Kadowaki, E Sasaki… - International Journal of …, 2021 - Springer
Background Until the emergence of immune checkpoint inhibitors, the EXTREME regimen
comprising platinum-based chemotherapy plus cetuximab was the standard of care for …

Predictors of outcome with cetuximab and paclitaxel for head and neck squamous cell carcinoma

B Pellini Ferreira, M Redman, KK Baker… - The …, 2017 - Wiley Online Library
Objectives Identify predictors of outcome in patients with recurrent/metastatic head and neck
squamous cell carcinoma (RMHNSCC) treated with weekly cetuximab and paclitaxel (CP) …