Major obstacles in the development of nanoformulations as efficient drug delivery systems
are the rapid clearance from blood circulation and lysosomal entrapment. To overcome …

A general strategy was developed to fabricate the chitosan-based micelles as smart drug
delivery system (DDS) for anti-cancer drug doxorubicin (DOX), via modulating the feeding …

In this study, a novel chitosan-based (CS) nanocarrier was developed for doxorubicin (DOX)
and oleanolic acid (OA) co-delivery. CS was first functionalized with folic acid to allow …

Natural polymers provide a better alternative to synthetic polymers in the domain of drug
delivery systems (DDSs) because of their renewability, biocompatibility, and low …

A novel intelligent nanocarrier with pH and redox sensitivities was developed based on
Carboxymethyl-chitosan (CMCS) and thioglycolic acid conjugated chitosan (TCS) to provide …

Facile one-pot approach was established to fabricate chitosan-based supramolecular
nanogels as pH/reduction dual-stimuli responsive drug delivery system (DDS) for anticancer …

To achieve effective intracellular anticancer drug release for boosted antitumor efficacy, the
acidity-responsive nanovehicles for doxorubicin (DOX) delivery were fabricated by tailor …

Three redox-sensitive nanocarriers were rationally designed based on amphiphilic low
molecular weight chitosan-cystamine-octylamine/dodecylamin/cetylamine (LC-Cys-OA, LC …

The morphology of the drug delivery systems (DDSs) has been recognized to play an
important role in their phagocytosis, cellular interaction and distribution. However, it is a …

The premature leakage of chemotherapeutics during delivery impedes drugs from entering
tumor cells, which produces considerable side effects in normal organs. Herein, we describe …