In animal models of cancer, oncologic imaging has evolved from a simple assessment of
tumor location and size to sophisticated multimodality exploration of molecular, physiologic …

Photoacoustic computed tomography (PACT), an emerging imaging modality in preclinical
cancer research, can provide multiparametric 3D information about structures, physiological …

The enormous advances in our understanding of the progression of diseases at the
molecular level have been supplemented by the new field of 'molecular imaging', which …

Imaging has become an indispensable tool in the study of cancer biology and in clinical
prognosis and treatment. The rapid advances in high resolution fluorescent imaging at …

The tumour microenvironment (TME) is a complex cellular ecosystem subjected to chemical
and physical signals that play a role in shaping tumour heterogeneity, invasion and …

The identification of genetic and biochemical mechanisms underlying tumor growth and
progression along with the unraveling of human genoma provided a plethora of new targets …

Molecular imaging fundamentally changes the way we look at cancer. Imaging paradigms
are now shifting away from classical morphological measures towards the assessment of …

Cancer is characterized by deregulation of cell proliferation and altered cell deathapoptosis,
which constitutes, in almost all instances, the minimal common platform upon which all …

The optical imaging plays an increasing role in preclinical studies, particularly in cancer
biology. The combined ultrasound and optical imaging, named photoacoustic imaging (PAI) …

Rationale: In vivo molecular imaging in preclinical animal models is a tool of choice for
understanding the pathophysiological mechanisms involved in cancer development and for …