Primordial germ cells nesting in the fetal testis give rise to gonocytes. The gonocytes then
transform into spermatogenic stem cells (SSCs) during the neonatal period and thereafter …

As the transient postnatal hormone surge in humans, known as 'minipuberty', occurs
simultaneously with key steps in germ-cell development, we investigated whether similar …

Sir, We greatly appreciate the Letter to the Editor by Bhartiya and colleagues and applaud
their efforts in writing this commentary, in response to the grand-theme review titled …

Purpose Undescended testis leads to infertility and malignancy resulting from aberrant germ
cell development. Androgens are proposed to control early germ cell development during …

The production of spermatozoa relies on a pool of spermatogonial stem cells (SSCs), formed
in infancy from the differentiation of their precursor cells, the gonocytes. Throughout adult …

PURPOSE: To elucidate the mechanism of infertility caused by cryptorchidism we focused
on early stage spermatogenesis and spermatogonial stem cell activity in undifferentiated …

With the recent publication of'Direct Differentiation of Human Pluripotent Stem Cells into
Haploid Spermatogenic Cells' in CELL REPORTS, several fundamental and clinical …

The human testis undergoes dramatic developmental and structural changes during
puberty, including proliferation and maturation of somatic niche cells, and the onset of …

In mammals, spermatogonial stem cells (SSCs) arise from a subpopulation of
prospermatogonia during neonatal testis development. Currently, molecular mechanisms …

Spermatogonial stem cells (SSCs) are a group of adult stem cells in the testis that serve as
the foundation of continuous spermatogenesis and male fertility. SSCs are capable of self …