Normal eating behaviour is coordinated by the tightly regulated balance between intestinal
and extra-intestinal homeostatic and hedonic mechanisms. By contrast, food addiction is a …

The obesity epidemic and its metabolic consequences are a major public health problem
both in the USA and globally. While the underlying causes are multifactorial, dysregulations …

In 2016, key studies have increased our understanding of the part played by the brain–gut–
microbiota axis in disorders as diverse as depression, obesity and autism spectrum disorder …

Background & Aims Based largely on results from preclinical studies, the concept of a brain
gut microbiome axis has been established, mediating bidirectional communication between …

The prevalence of obesity has risen to its highest values over the last two decades. While
many studies have either shown brain or microbiome connections to obesity, few have …

Obesity continues to be one of the major public health problems due to its high prevalence
and co-morbidities. Common co-morbidities not only include cardiometabolic disorders but …

Obesity is a global epidemic, placing socioeconomic strain on public healthcare systems,
especially within the so-called Western countries, such as Australia, United States, United …

The gut harbors an enormous diversity of microbes that are essential for the maintenance of
homeostasis in health and disease. A growing body of evidence supports the role of this …

The gut microbiota has the capacity to affect host appetite via intestinal satiety pathways, as
well as complex feeding behaviors. In this Review, we highlight recent evidence that the gut …

Interaction between the gut and the brain is essential for energy homeostasis. In obesity, this
homeostasis is disrupted, leading to a positive energy balance and weight gain. Obesity is a …