Since neuropathic pain is resistant to conventional analgesics such as opiates and non-
steroidal anti-inflammatory drugs, the development of new types of drugs for its treatment …

Treating neuropathic pain is a major clinical challenge, and several key molecules
associated with nociception have been suggested as potential targets for novel analgesics …

In an attempt to clarify whether glial cell line‐derived neurotrophic factor (GDNF), a survival
factor for subpopulations of primary afferent neurons, is involved in the states of neuropathic …

Glial cell line-derived neurotrophic factor (GDNF), a survival-promoting factor for a subset of
nociceptive small-diameter neurons, has been shown to exert analgesic effects on …

Neurotrophic factors, such as nerve growth factor and brain-derived neurotrophic factor, are
members of the structurally related neurotrophin family that play important roles in pain …

Introduction: Glial-derived neurotrophic factor (GDNF) and its family of ligands (GFLs) have
several functions in the nervous system. As a survival factor for dopaminergic neurons …

Introduction. An unfortunate consequence of incomplete nerve injury is development of
neuropathic pain and associated allodynia, a feeling of discomfort in response to benign …

The role of glial cell line-derived neurotrophic factor (GDNF) in nociceptive pathways is still
controversial, as both pronociceptive and antinociceptive actions have been reported. To …

Glial cell line-derived neurotrophic factor (GDNF) is necessary for the development of
sensory neurons, and appears to be critical for the survival of dorsal root ganglion (DRG) …

Neurotrophic factors have an established developmental role in regulating the survival and
specification of sensory neurons. However, these factors continue to exert an important …