[HTML][HTML] Combination strategies to enhance the efficacy of antimicrobial peptides against bacterial biofilms

L Grassi, G Maisetta, S Esin, G Batoni - Frontiers in Microbiology, 2017 - frontiersin.org
The great clinical significance of biofilm-associated infections and their inherent
recalcitrance to antibiotic treatment urgently demand the development of novel antibiofilm …

Potential application of antimicrobial peptides in the treatment of bacterial biofilm infections

N Strempel, J Strehmel… - Current pharmaceutical …, 2015 - ingentaconnect.com
The increasing prevalence of persistent biofilm infections, such as wound infections, chronic
lung infections or medical device-related infections, which usually tolerate conventional …

Use of antimicrobial peptides against microbial biofilms: advantages and limits

G Batoni, G Maisetta… - Current medicinal …, 2011 - ingentaconnect.com
The formation of surface-attached cellular agglomerates, the so-called biofilms, contributes
significantly to bacterial resistance to antibiotics and innate host defenses. Bacterial biofilms …

[HTML][HTML] Antimicrobial peptides and their interaction with biofilms of medically relevant bacteria

G Batoni, G Maisetta, S Esin - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
Biofilm-associated infections represent one of the major threats of modern medicine. Biofilm-
forming bacteria are encased in a complex mixture of extracellular polymeric substances …

[HTML][HTML] Antimicrobial peptides as an alternative for the eradication of bacterial biofilms of multi-drug resistant bacteria

JTC Pontes, AB Toledo Borges, CA Roque-Borda… - Pharmaceutics, 2022 - mdpi.com
Bacterial resistance is an emergency public health problem worldwide, compounded by the
ability of bacteria to form biofilms, mainly in seriously ill hospitalized patients. The World …

[HTML][HTML] Antimicrobial peptides as potential anti-biofilm agents against multidrug-resistant bacteria

PY Chung, R Khanum - Journal of microbiology, immunology and infection, 2017 - Elsevier
Bacterial resistance to commonly used drugs has become a global health problem, causing
increased infection cases and mortality rate. One of the main virulence determinants in many …

[HTML][HTML] Therapeutic potential of antimicrobial peptides in polymicrobial biofilm-associated infections

G Batoni, G Maisetta, S Esin - International Journal of Molecular Sciences, 2021 - mdpi.com
It is widely recognized that many chronic infections of the human body have a polymicrobial
etiology. These include diabetic foot ulcer infections, lung infections in cystic fibrosis …

A comprehensive guide on screening and selection of a suitable AMP against biofilm-forming bacteria

A Anurag Anand, A Amod, S Anwar… - Critical Reviews in …, 2023 - Taylor & Francis
Lately, antimicrobial resistance (AMR) is increasing at an exponential rate making it
important to search alternatives to antibiotics in order to combat multi-drug resistant (MDR) …

[HTML][HTML] Antimicrobial and antibiofilm peptides

A Di Somma, A Moretta, C Canè, A Cirillo, A Duilio - Biomolecules, 2020 - mdpi.com
The increasing onset of multidrug-resistant bacteria has propelled microbiology research
towards antimicrobial peptides as new possible antibiotics from natural sources …

Mechanisms of biofilm inhibition and degradation by antimicrobial peptides

L Segev-Zarko, R Saar-Dover, V Brumfeld… - Biochemical …, 2015 - portlandpress.com
Many bacteria live as biofilms to cope with unfavourable surroundings. Biofilms start from (i)
a planktonic stage,(ii) initial adhesion to surfaces and (iii) formation of sessile micro-colonies …