The SWI/SNF subunit BRG1 affects alternative splicing by changing RNA binding factor interactions with nascent RNA

A Gañez-Zapater, SD Mackowiak, Y Guo… - Molecular Genetics and …, 2022 - Springer
BRG1 and BRM are ATPase core subunits of the human SWI/SNF chromatin remodelling
complexes mainly associated with transcriptional initiation. They also have a role in …

The human SWI/SNF subunit Brm is a regulator of alternative splicing

E Batsché, M Yaniv, C Muchardt - Nature structural & molecular biology, 2006 - nature.com
The SWI/SNF (mating-type switch/sucrose nonfermenting) complex involved in chromatin
remodeling on promoters has also been detected on the coding region of genes. Here we …

SWI/SNF associates with nascent pre-mRNPs and regulates alternative pre-mRNA processing

A Tyagi, J Ryme, D Brodin, AK Östlund Farrants… - PLoS …, 2009 - journals.plos.org
The SWI/SNF chromatin remodeling complexes regulate the transcription of many genes by
remodeling nucleosomes at promoter regions. In Drosophila, SWI/SNF plays an important …

Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits

JR Raab, JS Runge, CC Spear, T Magnuson - Epigenetics & chromatin, 2017 - Springer
Background SWI/SNF is a large heterogeneous multi-subunit chromatin remodeling
complex. It consists of multiple sets of mutually exclusive components. Understanding how …

SR proteins and related factors in alternative splicing

S Lin, XD Fu - Alternative splicing in the postgenomic era, 2007 - Springer
SR proteins are a family of RNA binding proteins that contain a signature RS domain
enriched with serine/arginine repeats. The RS domain is also found in many other proteins …

The chromatin remodeling and mRNA splicing functions of the Brahma (SWI/SNF) complex are mediated by the SNR1/SNF5 regulatory subunit

CB Zraly, AK Dingwall - Nucleic acids research, 2012 - academic.oup.com
Nucleosome remodeling catalyzed by the ATP-dependent SWI/SNF complex is essential for
regulated gene expression. Transcriptome profiling studies in flies and mammals identified …

SWI/SNF regulates the alternative processing of a specific subset of pre-mRNAs in Drosophila melanogaster

J Waldholm, Z Wang, D Brodin, A Tyagi, S Yu… - BMC molecular …, 2011 - Springer
Abstract Background The SWI/SNF chromatin remodeling factors have the ability to remodel
nucleosomes and play essential roles in key developmental processes. SWI/SNF complexes …

Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes

S Sif, AJ Saurin, AN Imbalzano… - Genes & …, 2001 - genesdev.cshlp.org
Alteration of nucleosomes by ATP-dependent remodeling complexes represents a critical
step in the regulation of transcription. The human SWI/SNF (hSWI/SNF) family is composed …

Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins

A Crisci, F Raleff, I Bagdiul, M Raabe… - Nucleic acids …, 2015 - academic.oup.com
Abstract Splicing factor 1 (SF1) recognizes the branch point sequence (BPS) at the 3′
splice site during the formation of early complex E, thereby pre-bulging the BPS adenosine …

The superfamily of arginine/serine-rich splicing factors.

XD Fu - Rna, 1995 - ncbi.nlm.nih.gov
INTRODUCTION Pre-messenger RNA splicing requires small ribonucleo-protein particles
(snRNPs) and non-snRNP proteins. These factors are assembled onto pre-mRNA in an or …