Abstract Development of mobile composition of matter (MCM)-41 silica nanoparticles faces
challenges, eg surface charge properties, antigen loading efficiency, protecting from …

Mesoporous silica nanoparticles coated with Chitosan are exploited here as a potential
carrier for oral vaccine delivery. Bovine serum albumin (BSA) was used as a protein antigen …

To date there is no clinically approved adjuvant to drive a protective T-helper cell 17 (Th17)
immune response against Mycobacterium tuberculosis (Mtb). Trehalose Dimycolate (TDM) …

Oral delivery of protein or peptide drugs confronts several barriers, the intestinal epithelium
and the mucus barrier on the gastrointestinal tract is deemed to be the toughest obstacles …

Dendrimer-like mesoporous silica nanoparticles (MSNs) with large center-radial mesopores
have been prepared for macromolecular protein loading and delivery. Due to their unique …

Nanoparticles are excellent carriers for drug and protein, and have the potential to be used
in vaccine delivery system. Here, we prepared different structures silica nanoparticles such …

Although convenient, oral vaccination presents challenges due to low antigen stability and
limited targeting efficiency in the gastrointestinal (GI) tract. To address these issues, we …

Chitosan is a non-toxic biological material, but chitosan is insoluble in water, which hinders
the development and utilization of chitosan. Chitosan derivatives N-2-Hydroxypropyl …

Oral vaccines hold great promise for preventing major infectious diseases, but their
development is limited by various gastrointestinal tract (GIT) barriers and the low proportion …

Abstract Virus-like particles (VLPs), a kind of superior subunit vaccine, are assembled from
the viral structural proteins with similar capsids to viruses. However, the efficiency of cell …