Endothelial microparticles: a potential contribution to the thrombotic complications of the antiphospholipid syndrome

F Dignat-George, L Camoin-Jau… - Thrombosis and …, 2004 - thieme-connect.com
The antiphospholipid syndrome (APS) refers to persistent antiphospholipid antibodies (aPL)
associated with thrombotic and/or obstetrical complications. The endothelial cell is a target …

Circulating microparticles in patients with antiphospholipid antibodies: characterization and associations

S Chaturvedi, E Cockrell, R Espinola, L Hsi, S Fulton… - Thrombosis research, 2015 - Elsevier
The antiphospholipid syndrome is characterized by venous or arterial thrombosis and/or
recurrent fetal loss in the presence of circulating antiphospholipid antibodies. These …

Endothelial and platelet microparticles in patients with antiphospholipid antibodies

KA Breen, K Sanchez, N Kirkman, PT Seed… - Thrombosis research, 2015 - Elsevier
Background The antiphospholipid syndrome (APS) is the association of thrombosis and
recurrent pregnancy loss and/or pregnancy morbidity with persistent antiphospholipid …

In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant

V Combes, AC Simon, GE Grau… - The Journal of …, 1999 - Am Soc Clin Investig
Microparticles (MPs) resulting from vesiculation of platelets and other blood cells have been
extensively documented in vitro and have been found in increased numbers in several …

Studies of microparticles in patients with the antiphospholipid syndrome (APS)

A Vikerfors, F Mobarrez, K Bremme, M Holmström… - Lupus, 2012 - journals.sagepub.com
Objectives: To study circulating platelet, monocyte and endothelial microparticles (PMPs,
MMPs and EMPs) in patients with antiphospholipid syndrome (APS) in comparison with …

Circulating platelet-derived microparticles in systemic lupus erythematosus

J Pereira, G Alfaro, M Goycoolea… - Thrombosis and …, 2006 - thieme-connect.com
The risk for thrombosis is significantly increased in systemic lupus erythematosus (SLE),
affecting both venous and arterial vessels. Activated platelets are known to participate in …

[HTML][HTML] Antigenic characterization of endothelial cell-derived microparticles and their detection ex vivo

MNA Hussein, EW Meesters, N Osmanovic… - Journal of Thrombosis …, 2003 - Elsevier
Background: Endothelial activation and dysfunction are associated with several diseases.
However, hardly any specific markers are available. Microparticles (MP) from endothelial …

Elevation of endothelial microparticles, platelets, and leukocyte activation in patients with venous thromboembolism

JA Chirinos, GA Heresi, H Velasquez, W Jy… - Journal of the American …, 2005 - jacc.org
Objectives: The purpose of this research was to determine the levels of platelet, leukocyte,
and endothelial activation and markers of cellular interactions in patients with venous …

Phospholipid composition of in vitro endothelial microparticles and their in vivo thrombogenic properties

MNA Hussein, AN Böing, É Biró, FJ Hoek… - Thrombosis research, 2008 - Elsevier
INTRODUCTION: Microparticles from activated endothelial cells (EMP) are well known to
expose tissue factor (TF) and initiate coagulation in vitro. TF coagulant activity is critically …

Release of neutrophil extracellular traps by neutrophils stimulated with antiphospholipid antibodies: a newly identified mechanism of thrombosis in the …

S Yalavarthi, TJ Gould, AN Rao, LF Mazza… - Arthritis & …, 2015 - Wiley Online Library
Objective Antiphospholipid antibodies (aPL), especially those targeting β2‐glycoprotein I
(β2GPI), are well known to activate endothelial cells, monocytes, and platelets, with …