We are constantly exposed to the threat of fungal infection. The outcome—clearance,
commensalism or infection—depends largely on the ability of our innate immune defences …

Fungal pathogenesis is by definition a situation in which a fungal species is successfully
surviving in host tissues and causing local destruction or toxicity. The immune system is …

A restricted number of antifungal agents are available for the therapy of fungal diseases.
With the introduction of epidemiological cut-off values for each agent in important fungal …

Opportunistic fungal pathogens can cause a diverse range of diseases in humans. The
increasing rate of fungal infections caused by strains that are resistant to commonly used …

Fungal infections are a serious global concern because of their ability to spread and
colonize host tissues in immunocompromised individuals. Such infections have been …

Fungal infections are increasing globally, causing alarmingly high mortality and economic
burden. In addition to antifungal resistance, other more subtle drug responses appear to …

In the last years, the clinical relevance of fungal diseases has gained importance because of
an increasing population of immunocompromised hosts, such as patients who have …

Fungi are eukaryotic heterotrophs present in virtually every environment, with potentially
more than 5 million individual species (1). Despite this impressive biodiversity, only about …

The global burden of fungal disease poses a substantial threat to human, animal, and
environmental health, endangering both human and livestock populations and creating …

Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …