A multi-center study on safety and efficacy of immune checkpoint inhibitors in cancer patients with kidney transplant

N Murakami, P Mulvaney, M Danesh, A Abudayyeh… - Kidney international, 2021 - Elsevier
Immune checkpoint inhibitors (ICIs) are widely used for various malignancies. However,
their safety and efficacy in patients with a kidney transplant have not been defined. To …

[HTML][HTML] Systematic review of the safety of immune checkpoint inhibitors among kidney transplant patients

S Manohar, C Thongprayoon… - Kidney international …, 2020 - Elsevier
Introduction Kidney transplant (Ktx) recipients are excluded from clinical trials of immune
checkpoint inhibitors. The aim of this systematic review was to assess the safety of immune …

Immune checkpoint inhibitors in kidney transplant recipients: a multicentre, single-arm, phase 1 study

RP Carroll, M Boyer, V Gebski, B Hockley… - The Lancet …, 2022 - thelancet.com
Background Most kidney transplant recipients with cancer stop or reduce
immunosuppressive therapy before starting treatment with an immune checkpoint inhibitor …

The safety and efficacy of checkpoint inhibitors in transplant recipients: a case series and systematic review of literature

V Kumar, AB Shinagare, HG Rennke, S Ghai… - The …, 2020 - academic.oup.com
Limited data exist on safety and efficacy of immune checkpoint inhibitors (ICIs) among organ
transplant recipients. The objective of this study was to report a case series of two patients …

Kidney complications of immune checkpoint inhibitors: a review

R Shingarev, IG Glezerman - American Journal of Kidney Diseases, 2019 - Elsevier
Immunologic control of malignancy has long been recognized as an important determinant
of disease progression. Recent advances in immunology have led to the focus on several …

[HTML][HTML] Transplant rejections associated with immune checkpoint inhibitors: a pharmacovigilance study and systematic literature review

LS Nguyen, S Ortuno, B Lebrun-Vignes… - European Journal of …, 2021 - Elsevier
Background Solid organ transplant recipients are at increased risk of cancer due to long-
term immunosuppression. Immune-checkpoint inhibitors (ICI) showed clinical benefits but …

Immune checkpoint inhibitor use in solid organ transplant recipients: a systematic review

AJ Portuguese, SS Tykodi, CD Blosser… - Journal of the National …, 2022 - jnccn.org
Chronic immunosuppression in solid organ transplant recipients (SOTRs) leads to an
increased risk of a wide variety of cancers. Immune checkpoint inhibitor (ICI) therapy is …

[HTML][HTML] Efficacy and tolerance of immune checkpoint inhibitors in transplant patients with cancer: a systematic review

T d'Izarny-Gargas, A Durrbach, M Zaidan - American Journal of …, 2020 - Elsevier
Solid organ transplant (SOT) is frequently complicated by cancers, which render
immunosuppression challenging. Immune checkpoint inhibitors have emerged as …

Renal complications of immune checkpoint blockade

N Murakami, S Motwani, LV Riella - Current problems in cancer, 2017 - Elsevier
Immune checkpoint inhibitors have been approved for a variety of cancer species. Renal
complications in use of these agents are not very common compared with other immune …

[HTML][HTML] Immune checkpoint inhibitors and immune-related adverse renal events

SM Herrmann, MA Perazella - Kidney international reports, 2020 - Elsevier
Renal toxicities have been increasingly recognized as complications of the immune
checkpoint inhibitors (ICIs). Recent studies have outlined the incidence and potential risk …