[HTML][HTML] Extracellular vesicles in the development of cancer therapeutics

H Sun, S Burrola, J Wu, WQ Ding - International journal of molecular …, 2020 - mdpi.com
Extracellular vesicles (EVs) are small lipid bilayer-delimited nanoparticles released from all
types of cells examined thus far. Several groups of EVs, including exosomes, microvesicles …

[HTML][HTML] The function and clinical application of extracellular vesicles in innate immune regulation

X Zhou, F Xie, L Wang, L Zhang, S Zhang… - Cellular & molecular …, 2020 - nature.com
The innate immune system plays a crucial role in the host defense against viral and
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …

Engineered extracellular vesicles for cancer therapy

X Zhang, H Zhang, J Gu, J Zhang, H Shi… - Advanced …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …

[HTML][HTML] Extracellular vesicles: emerging targets for cancer therapy

P Vader, XO Breakefield, MJA Wood - Trends in molecular medicine, 2014 - cell.com
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are
released by almost all cell types, including tumour cells. Through transfer of their molecular …

[HTML][HTML] Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy

MK Jayasinghe, M Pirisinu, Y Yang, B Peng… - Theranostics, 2022 - ncbi.nlm.nih.gov
The advent of novel therapeutics in recent years has urged the need for a safe, non-
immunogenic drug delivery vector capable of delivering therapeutic payloads specifically to …

New insights into the biological impacts of immune cell-derived exosomes within the tumor environment

M Shen, X Ren - Cancer letters, 2018 - Elsevier
Exosomes are a group of nano-sized membrane vesicles that transfer proteins, nucleic
acids, and lipids to nearby and faraway cells, playing an important role in the intercellular …

Extracellular vesicles-based drug delivery system for cancer treatment

B Balachandran, Y Yuana - Cogent Medicine, 2019 - Taylor & Francis
The decrease in cancer mortality indicates an improvement in cancer treatment and
management. One strategy that has been a focus in cancer treatment is development of drug …

Extracellular vesicles in cancer therapy

SE Wang - Seminars in cancer biology, 2022 - Elsevier
Extracellular vesicles (EVs), including a variety of membrane-enclosed nanosized particles
carrying cell-derived cargo, mediate a major type of intercellular communication in …

Professional killers: The role of extracellular vesicles in the reciprocal interactions between natural killer, CD8+ cytotoxic T‐cells and tumour cells

F Del Vecchio, V Martinez‐Rodriguez… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) mediate the cross‐talk between cancer cells and the cells of the
surrounding Tumour Microenvironment (TME). Professional killer cells include Natural Killer …

Modularized extracellular vesicles: the dawn of prospective personalized and precision medicine

SC Tao, SC Guo, CQ Zhang - Advanced Science, 2018 - Wiley Online Library
Extracellular vesicles (EVs) are ubiquitous nanosized membrane vesicles consisting of a
lipid bilayer enclosing proteins and nucleic acids, which are active in intercellular …