Colorectal cancer is the second leading cause of cancer death worldwide. Significant
advances in the molecular mechanisms underlying colorectal cancer have been made; …

Simple Summary Organoids, also known as self-organized 3D organ-like clusters, represent
almost a physiological system for studying cells, stem cells, tissues, and diseases, especially …

Patient‐derived organoids are gaining incremental popularity in both basic sciences and
translational applications toward precision medicine and revolutionized drug discovery …

As the importance of organoids increases, the need to develop organoid culture systems
suitable for basic biological and clinical applications is being emphasized. However, there is …

Currently, colorectal cancer is still the third leading cause of cancer-related mortality, and the
incidence is rising. It is a long time since the researchers used cancer cell lines and animals …

In vitro cell culture models are emerging as promising tools to understand human
development, disease progression, and provide reliable, rapid and cost-effective results for …

Patient derived organoids have emerged as robust preclinical models for screening anti-
cancer therapeutics. Current 2D culturing methods do not provide physiological responses …

The conventional microwell-based platform for construction of organoid models exhibits
limitations in precision oncology applications because of low-speed growth and high …

Stem-cell-derived epithelial organoids are routinely used for the biological and biomedical
modelling of tissues. However, the complexity, lack of standardization and quality control of …

Tumor organoids are 3D cultures of cancer cells that can be derived on an individual patient
basis with a high success rate. This creates opportunities to build large biobanks with …