Identification of a glycosyltransferase signature for predicting prognosis and immune microenvironment in neuroblastoma

Y Sha, L Han, B Sun, Q Zhao - Frontiers in cell and developmental …, 2022 - frontiersin.org
Neuroblastoma (NB) is one of the most common solid tumors in children.
Glycosyltransferases (GTs) play a crucial role in tumor development and immune escape …

[HTML][HTML] A novel ganglioside-related risk signature can reveal the distinct immune landscape of neuroblastoma and predict the immunotherapeutic response

J Yang, L Han, Y Sha, Y Jin, Z Li, B Gong, J Li… - Frontiers in …, 2022 - frontiersin.org
Introduction Gangliosides play an essential role in cancer development and progression.
However, the involvement of gangliosides in the prognosis and tumor microenvironment …

A glycosylation-related gene signature predicts prognosis, immune microenvironment infiltration, and drug sensitivity in glioma

Y Yang, H Teng, Y Zhang, F Wang, L Tang… - Frontiers in …, 2024 - frontiersin.org
Glioma represents the most common primary cancer of the central nervous system in adults.
Glycosylation is a prevalent post-translational modification that occurs in eukaryotic cells …

A promising glycolysis-and immune-related prognostic signature for glioblastoma

F Wang, X Liu, H Jiang, B Chen - World Neurosurgery, 2022 - Elsevier
Background Glioblastoma multiforme (GBM) is a malignant brain tumor with a poor
prognosis. Aerobic glycolysis and an immunosuppressive microenvironment are potentially …

Predictive potentials of glycosylation-related genes in glioma prognosis and their correlation with immune infiltration

YF Sun, LC Zhang, RZ Niu, L Chen, QJ Xia… - Scientific Reports, 2024 - nature.com
Glycosylation is currently considered to be an important hallmark of cancer. However, the
characterization of glycosylation-related gene sets has not been comprehensively analyzed …

Glioblastoma glycolytic signature predicts unfavorable prognosis, immunological heterogeneity, and ENO1 promotes microglia M2 polarization and cancer cell …

X Liang, Z Wang, Z Dai, H Zhang, J Zhang, P Luo… - Cancer Gene …, 2023 - nature.com
Glioblastomas are the most malignant brain tumors, whose progress was promoted by
aberrate aerobic glycolysis. The immune environment was highly engaged in glioblastoma …

Glycosylation modification patterns reveal distinct tumor metabolism and immune microenvironment landscape in lower-grade gliomas

G Tang, L Tan, H Yuan, W Yin - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Glycosylation alterations, a key driver throughout tumorigenesis and tumor progression,
could regulate the microenvironment and immune response as well as lead to harmful …

Serine and glycine metabolism-related gene expression signature stratifies immune profiles of brain gliomas, and predicts prognosis and responses to …

S Chen, S Zhang, W Feng, J Li, Y Yuan, W Li… - Frontiers in …, 2022 - frontiersin.org
Glioma is one of the most lethal cancers and causes more than 200,000 deaths every year.
Immunotherapy was an inspiring therapy for multiple cancers but failed in glioma treatment …

Deciphering glycosylation-driven prognostic insights and therapeutic prospects in glioblastoma through a comprehensive regulatory model

X Jin, Z Chen, H Zhao - Frontiers in Oncology, 2024 - frontiersin.org
The oncogenesis and development of glioblastoma multiforme have been linked to
glycosylation modifications, which are common post-translational protein modifications …

GRN is a prognostic biomarker and correlated with immune infiltration in glioma: A study based on TCGA data

SM Xu, HY Xiao, ZX Hu, XF Zhong, YJ Zeng… - Frontiers in …, 2023 - frontiersin.org
Background Among primary brain tumors, gliomas are associated with a poor prognosis and
a median survival that varies depending on the tumor grade and subtype. As the most …