Alzheimer's disease (AD) is a neurodegenerative disorder which leads to mental
deterioration due to aberrant accretion of misfolded proteins in the brain. According to …

Mitochondrial dysfunction plays a very vital role in the pathogenesis of Alzheimer's disease
(AD). Several shreds of evidence have indicated that the mitochondrial function is severely …

Alzheimer's disease (AD) is a major cause of dementia in older adults and is fast becoming
a major societal and economic burden due to an increase in life expectancy. Age seems to …

Alzheimer's disease (AD) is the most frequent cause of age-related neurodegeneration and
cognitive impairment, and there are currently no broadly effective therapies. The underlying …

Neurodegenerative diseases are intricate in nature because of the involvement of the
multiple pathophysiological events including mitochondrial dysfunction, neuroinflammation …

Highlights•Mitochondria decide the progression of Alzheimer's disease.•AD pathology and
severity are determined by mitochondrial dynamics and energetic mechanisms.•Mitophagy …

Neuronal transmission and functional synapses require mitochondria, which are mainly
involved in the generation of energy (ATP and NAD+), regulation of cell signaling and …

Alzheimer disease (AD) is a progressive and deleterious neurodegenerative disorder that
affects mostly the elderly population. At the moment, no effective treatments are available in …

As the population ages, the incidence of neurodegenerative diseases is increasing. Due to
intensive research, important steps in the elucidation of pathogenetic cascades have been …

Alzheimer's disease (AD) is a complex, progressive, and irreversible neurodegenerative
disorder. Recent reports suggest that it affects more than 36 million people worldwide and …