T-dependent humoral responses generate long-lived memory B cells and plasma cells
(PCs) predominantly through germinal center (GC) reaction. In human and mouse, memory …

There is little insight into or agreement about the signals that control differentiation of
memory B cells (MBCs) and long-lived plasma cells (LLPCs). By performing BrdU pulse …

Memory B cells comprise a heterogenous group of cells that differ in origin and phenotype.
During the early phases of the immune response, activated B cells can differentiate into IgM …

Germinal centers (GCs) are generally considered to be the sole site of memory B‐cell
generation. However, recent studies demonstrate that memory B cells can also develop in …

Memory B cells (MBCs) are phenotypically and functionally diverse, but their developmental
origins remain undefined. Murine MBCs can be divided into subsets by expression of CD80 …

Switched and IgM memory B cells execute different and noninterchangeable functions. We
studied memory B cells in children of different ages, in peripheral blood and spleen and …

B-cell memory describes the populations of cells that provide long-term humoral immunity:
long-lived antibody-secreting plasma cells that reside mainly in the bone marrow and …

Immunization with a T cell–dependent antigen elicits production of specific memory B cells
and antibody-secreting cells (ASCs). The kinetic and developmental relationships between …

One component of memory in the antibody system is long-lived memory B cells selected for
the expression of somatically mutated, high-affinity antibodies in the T cell–dependent …

Memory is the defining feature of the adaptive immune system. Humoral immune memory is
largely though not exclusively generated in the germinal center (GC), which spawns long …