Effect of a novel nasal oxytocin spray with enhanced bioavailability on autism: a randomized trial

H Yamasue, M Kojima, H Kuwabara, M Kuroda… - Brain, 2022 - academic.oup.com
Although intranasal oxytocin is expected to be a novel therapy for the core symptoms of
autism spectrum disorder, which has currently no approved medication, the efficacy of …

The potential of nasal oxytocin administration for remediation of autism spectrum disorders

Y Okamoto, M Ishitobi, Y Wada… - CNS & Neurological …, 2016 - ingentaconnect.com
Administration of oxytocin has been proposed as a treatment for the core symptoms of
autism spectrum disorder (ASD), including social-communicative deficit. Previous clinical …

[HTML][HTML] Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial

E Anagnostou, L Soorya, W Chaplin, J Bartz… - Molecular autism, 2012 - Springer
Background There are no effective medications for the treatment of social cognition/function
deficits in autism spectrum disorder (ASD), and adult intervention literature in this area is …

[HTML][HTML] Dose-dependent social-cognitive effects of intranasal oxytocin delivered with novel Breath Powered device in adults with autism spectrum disorder: a …

DS Quintana, LT Westlye, S Hope, T Naerland… - Translational …, 2017 - nature.com
The neuropeptide oxytocin has shown promise as a treatment for symptoms of autism
spectrum disorders (ASD). However, clinical research progress has been hampered by a …

Systematic review and meta‐analysis of reported adverse events of long‐term intranasal oxytocin treatment for autism spectrum disorder

Q Cai, L Feng, KZ Yap - Psychiatry and clinical neurosciences, 2018 - Wiley Online Library
Recent studies have suggested oxytocin as a possible drug to treat social deficits caused by
autism spectrum disorder (ASD), but the safety of intranasal oxytocin in autistic patients has …

Long-term administration of intranasal oxytocin is a safe and promising therapy for early adolescent boys with autism spectrum disorders

M Tachibana, K Kagitani-Shimono, I Mohri… - Journal of child and …, 2013 - liebertpub.com
Objective: Oxytocin (OT) has been a candidate for the treatment of autism spectrum
disorders (ASD), and the impact of intranasally delivered OT on ASD has been investigated …

Promising evidence and remaining issues regarding the clinical application of oxytocin in autism spectrum disorders

H Yamasue - Psychiatry and clinical neurosciences, 2016 - Wiley Online Library
Oxytocin is a potential therapeutic for the core symptoms of autism spectrum disorder (ASD),
which is currently untreatable with pharmacotherapy. Previous clinical trials of a single dose …

[HTML][HTML] Behavioral effects of multiple-dose oxytocin treatment in autism: a randomized, placebo-controlled trial with long-term follow-up

S Bernaerts, B Boets, G Bosmans, J Steyaert, K Alaerts - Molecular autism, 2020 - Springer
Background Intranasal administration of the “prosocial” neuropeptide oxytocin is
increasingly explored as a potential treatment for targeting the core characteristics of autism …

Changes in endogenous oxytocin levels after intranasal oxytocin treatment in adult men with autism: An exploratory study with long-term follow-up

K Alaerts, J Steyaert, B Vanaudenaerde… - European …, 2021 - Elsevier
Intranasal administration of the neuropeptide oxytocin (OT) is increasingly explored as a
potential treatment for targeting the core symptoms of autism spectrum disorder (ASD) …

Beyond the hype and hope: Critical considerations for intranasal oxytocin research in autism spectrum disorder

GA Alvares, DS Quintana, AJO Whitehouse - Autism Research, 2017 - Wiley Online Library
Extensive research efforts in the last decade have been expended into understanding
whether intranasal oxytocin may be an effective therapeutic in treating social communication …